(Q47927278)

6 February 2018

title

Drosophila presenilin is required for neuronal differentiation and affects notch subcellular localization and signaling (English)

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6 February 2018

author name string

Guo Y

1

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6 February 2018

Livne-Bar I

2

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6 February 2018

Zhou L

3

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6 February 2018

Boulianne GL

4

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6 February 2018

language of work or name

English

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publication date

1 October 1999

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6 February 2018

published in

Journal of Neuroscience

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6 February 2018

volume

19

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6 February 2018

issue

19

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6 February 2018

page(s)

8435-8442

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6 February 2018

Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function

cites work

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12 December 2020

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

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Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development.

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Characterization and spatial distribution of the ELAV protein duringDrosophila melanogaster development

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Cell surface expression of the Alzheimer disease-related presenilin proteins

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Structure and distribution of the Notch protein in developing Drosophila.

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12 December 2020

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

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Isolation and characterization of Drosophila presenilin homolog.

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12 December 2020

The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum

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12 December 2020

Nuclear access and action of notch in vivo

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12 December 2020

The Notch1 receptor is cleaved constitutively by a furin-like convertase

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12 December 2020

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

1 reference

12 December 2020

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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12 December 2020

Cloning and characterization of the Drosophila presenilin homologue.

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

1 reference

12 December 2020

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

1 reference

12 December 2020

Developmental regulation of presenilin mRNA expression parallels notch expression.

1 reference

12 December 2020

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1 reference

12 December 2020

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

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12 December 2020

Presenilin is required for activity and nuclear access of Notch in Drosophila

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12 December 2020

Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

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12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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12 December 2020

Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila.

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12 December 2020

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

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12 December 2020

Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

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12 December 2020

Transposition of cloned P elements into Drosophila germ line chromosomes.

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12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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12 December 2020

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

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12 December 2020

Effects of SEL-12 presenilin on LIN-12 localization and function in Caenorhabditis elegans.

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12 December 2020

Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.

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12 December 2020

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

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12 December 2020

The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages.

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12 December 2020

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

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12 December 2020

Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

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12 December 2020

Characterization of Drosophila Presenilin and its colocalization with Notch during development

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12 December 2020

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

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12 December 2020

Skeletal and CNS defects in Presenilin-1-deficient mice

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12 December 2020

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

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12 December 2020

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

12 December 2020

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

12 December 2020

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

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12 December 2020

Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing

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12 December 2020

Identifiers

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6 February 2018