(Q47948580)

7 February 2018

title

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia (English)

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7 February 2018

microvasculature remodeling

main subject

hypoxia

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pulmonary hypertension

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based on heuristic

inferred from title

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5

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7 February 2018

author name string

Hideyuki Beppu

1

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7 February 2018

Fumito Ichinose

2

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7 February 2018

Noriko Kawai

3

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7 February 2018

Rosemary C Jones

4

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7 February 2018

Warren M Zapol

6

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7 February 2018

Kohei Miyazono

7

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7 February 2018

En Li

8

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7 February 2018

Kenneth D Bloch

9

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7 February 2018

publication date

30 July 2004

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7 February 2018

American Journal of Physiology - Lung Cellular and Molecular Physiology

published in

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7 February 2018

volume

287

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7 February 2018

issue

6

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7 February 2018

page(s)

L1241-7

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7 February 2018

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

BMP type II receptor is required for gastrulation and early development of mouse embryos

21 January 2018

1 reference

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Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 January 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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Signaling molecules in nonfamilial pulmonary hypertension

21 January 2018

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S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction

21 January 2018

1 reference

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alpha-smooth-muscle actin and microvascular precursor smooth-muscle cells in pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Divergence and convergence of TGF-beta/BMP signaling

21 January 2018

1 reference

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Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

21 January 2018

1 reference

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Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred

21 January 2018

1 reference

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Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Developmental paradigms in terminal lung development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

21 January 2018

1 reference

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Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.

21 January 2018

1 reference

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Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00239.2004

10.1152/AJPLUNG.00239.2004

21 January 2018

Identifiers

DOI

1 reference

7 February 2018

1 reference

7 February 2018