(Q47959586)

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Improved retinal ganglion cell survival through retinal microglia suppression by a chinese herb extract, triptolide, in the DBA/2J mouse model of glaucoma

scientific article published on 22 July 2013

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

Improved retinal ganglion cell survival through retinal microglia suppression by a chinese herb extract, triptolide, in the DBA/2J mouse model of glaucoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

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retinal ganglion cell

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based on heuristic

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author name string

Fan Yang

1

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

Lingling Wu

2

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

Xiujuan Guo

3

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

Dongmei Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

Ying Li

5

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

publication date

22 July 2013

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

Ocular Immunology and Inflammation

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

21

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

5

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

378-389

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

The number of people with glaucoma worldwide in 2010 and 2020

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Immune regulation toward immunomodulation for neuroprotection in glaucoma

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The immune system and glaucoma

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Is primary open-angle glaucoma part of a generalized sensory neurodegeneration? A review of the evidence

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Neuroprotection in glaucoma: recent and future directions

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Cell transplantation approaches to retinal ganglion cell neuroprotection in glaucoma.

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Neuroprotective role of the innate immune system by microglia

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Microglia and neurodegeneration: the role of systemic inflammation.

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Changing face of microglia

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Microglia in health and disease

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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The role of microglial cell subsets in Alzheimer's disease

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Transforming growth factor-β stimulates β amyloid uptake by microglia through Smad3-dependent mechanisms.

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Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.

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Involvement of the CD200 receptor complex in microglia activation in experimental glaucoma

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Glial modulation of retinal ganglion cell death in glaucoma

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Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

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21 January 2018

Triptolide in the treatment of psoriasis and other immune-mediated inflammatory diseases

1 reference

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21 January 2018

Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis

1 reference

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21 January 2018

Triptolide inhibits colon-rectal cancer cells proliferation by induction of G1 phase arrest through upregulation of p21.

1 reference

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21 January 2018

Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f.

1 reference

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21 January 2018

Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F.

1 reference

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21 January 2018

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

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21 January 2018

Triptolide protects dopaminergic neurons from inflammation-mediated damage induced by lipopolysaccharide intranigral injection

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21 January 2018

Triptolide, a Chinese herbal extract, protects dopaminergic neurons from inflammation-mediated damage through inhibition of microglial activation

1 reference

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21 January 2018

Triptolide inhibits amyloid-beta1-42-induced TNF-alpha and IL-1beta production in cultured rat microglia

1 reference

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21 January 2018

Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration

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21 January 2018

Treatment of db/db diabetic mice with triptolide: a novel therapy for diabetic nephropathy

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21 January 2018

Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD

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21 January 2018

Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo

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21 January 2018

A novel role for Sema3A in neuroprotection from injury mediated by activated microglia.

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21 January 2018

Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma.

1 reference

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21 January 2018

Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking

1 reference

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21 January 2018

Retinal neurodegeneration in the DBA/2J mouse-a model for ocular hypertension.

1 reference

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Microglial activation in the visual pathway in experimental glaucoma: spatiotemporal characterization and correlation with axonal injury

1 reference

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Friend or foe? Resolving the impact of glial responses in glaucoma

1 reference

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Early microglia activation in a mouse model of chronic glaucoma

1 reference

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Retinal-cell-conditioned medium prevents TNF-alpha-induced apoptosis of purified ganglion cells

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Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma.

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Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma

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Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma

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Dependency of intraocular pressure elevation and glaucomatous changes in DBA/2J and DBA/2J-Rj mice

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21 January 2018

Identifiers

10.3109/09273948.2013.806989

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/23876132

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