(Q47967532)

7 February 2018

title

A pharmacokinetic, pharmacodynamic, and electrocardiographic study of liposomal mifamurtide (L-MTP-PE) in healthy adult volunteers (English)

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7 February 2018

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Karthik Venkatakrishnan

1

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7 February 2018

William G Kramer

2

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7 February 2018

Timothy W Synold

3

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7 February 2018

Daniel B Goodman

4

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7 February 2018

Evin Sides

5

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7 February 2018

Cristina Oliva

6

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7 February 2018

publication date

30 March 2012

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7 February 2018

European Journal of Clinical Pharmacology

published in

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7 February 2018

volume

68

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7 February 2018

issue

10

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7 February 2018

page(s)

1347-1355

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7 February 2018

https://scigraph.springernature.com/pub.10.1007/s00228-012-1262-1

exact match

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cites work

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

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Therapy for osteosarcoma in dogs with intravenous injection of liposome-encapsulated muramyl tripeptide

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00228-012-1262-1

Phase I trial of liposomal muramyl tripeptide phosphatidylethanolamine in cancer patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00228-012-1262-1

Phase II study of liposomal muramyl tripeptide phosphatidylethanolamine (MTP/PE) in advanced soft tissue sarcomas of the adult. An EORTC Soft Tissue and Bone Sarcoma Group study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-012-1262-1

Phase II study of liposomal muramyl tripeptide in osteosarcoma: the cytokine cascade and monocyte activation following administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-012-1262-1

Pharmacokinetics and immunomodulatory effects on monocytes during prolonged therapy with liposomal muramyltripeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-012-1262-1

Osteosarcoma: a randomized, prospective trial of the addition of ifosfamide and/or muramyl tripeptide to cisplatin, doxorubicin, and high-dose methotrexate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-012-1262-1

Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group

21 January 2018

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Molecularly targeted oncology therapeutics and prolongation of the QT interval

21 January 2018

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Near-thorough QT study as part of a first-in-man study

21 January 2018

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12 December 2020

Liposomal muramyl tripeptide up-regulates interleukin-1 alpha, interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 gene expression in human monocytes

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12 December 2020

Initial clinical trial of the macrophage activator muramyl tripeptide-phosphatidylethanolamine encapsulated in liposomes in patients with advanced cancer

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12 December 2020

Liposomal muramyl tripeptide upregulates adhesion molecules on the surface of human monocytes

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12 December 2020

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

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12 December 2020

Challenges of characterizing proarrhythmic risk due to QTc prolongation induced by nonadjuvant anticancer agents

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12 December 2020

Phase I and immunomodulatory study of a muramyl peptide, muramyl tripeptide phosphatidylethanolamine

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12 December 2020

Therapy of cancer metastasis by systemic activation of macrophages

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12 December 2020

Activation of tumoricidal properties in human blood monocytes by liposomes containing lipophilic muramyl tripeptide

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12 December 2020

Adjuvant therapy for osteosarcoma in dogs: results of randomized clinical trials using combined liposome-encapsulated muramyl tripeptide and cisplatin

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12 December 2020

Optimization and limitations of systemic treatment of murine melanoma metastases with liposomes containing muramyl tripeptide phosphatidylethanolamine

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12 December 2020

Liposome-encapsulated MTP-PE: a novel biologic agent for cancer therapy

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12 December 2020

Isolation of tumoricidal macrophages from lung melanoma metastases of mice treated systemically with liposomes containing a lipophilic derivative of muramyl dipeptide

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12 December 2020

10.1007/S00228-012-1262-1

Identifiers

DOI

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7 February 2018

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7 February 2018