(Q47975683)

7 February 2018

review article

1 reference

title

Bone morphogenetic proteins: from basic studies to clinical approaches (English)

1 reference

7 February 2018

1 reference

Sakou T

1

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7 February 2018

publication date

1 June 1998

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7 February 2018

published in

Bone

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7 February 2018

volume

22

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7 February 2018

issue

6

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7 February 2018

page(s)

591-603

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7 February 2018

Potent ectopic bone-inducing activity of bone morphogenetic protein-4/7 heterodimer

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7 January 2021

Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria

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7 January 2021

Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells.

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7 January 2021

Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

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7 January 2021

Signal transduction by members of the transforming growth factor-beta superfamily

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7 January 2021

Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions

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7 January 2021

Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing

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7 January 2021

Expression of bone morphogenetic protein-6 messenger RNA in bovine growth plate chondrocytes of different size

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7 January 2021

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone

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7 January 2021

Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP-2B) and modulation by transforming growth factor beta 1 and beta 2.

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7 January 2021

Bone morphogenetic protein-2b stimulation of growth and osteogenic phenotypes in rat osteoblast-like cells: comparison with TGF-beta 1.

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7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

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7 January 2021

The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects

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7 January 2021

In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusions

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7 January 2021

Osteogenin and recombinant bone morphogenetic protein 2B are chemotactic for human monocytes and stimulate transforming growth factor beta 1 mRNA expression

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7 January 2021

Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3

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7 January 2021

A common plan for dorsoventral patterning in Bilateria

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7 January 2021

TGF-beta-receptor-mediated signaling

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7 January 2021

Intracellular signalling: the mad way to do it.

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7 January 2021

Opposite effects of osteogenic protein and transforming growth factor beta on chondrogenesis in cultured long bone rudiments.

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7 January 2021

Growth differentiation factor-9 is required during early ovarian folliculogenesis

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7 January 2021

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye

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7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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7 January 2021

The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4.

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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7 January 2021

Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells.

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7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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7 January 2021

Bone-inducing activity of mature BMP-2b produced from a hybrid BMP-2a/2b precursor

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7 January 2021

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7 January 2021

Expression and localization of bone morphogenetic proteins (BMPs) and BMP receptors in ossification of the ligamentum flavum

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic proteins (BMP-2 and BMP-3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic MC3T3-E1 cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

1 reference

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7 January 2021

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin.

1 reference

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7 January 2021

The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor.

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7 January 2021

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7 January 2021

Fibroblasts of spinal ligaments pathologically differentiate into chondrocytes induced by recombinant human bone morphogenetic protein-2: morphological examinations for ossification of spinal ligaments

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7 January 2021

Recombinant human growth/differentiation factor 5 stimulates mesenchyme aggregation and chondrogenesis responsible for the skeletal development of limbs.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Differential chemotactic responses of different populations of fetal rat calvaria cells to platelet-derived growth factor and transforming growth factor beta

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7 January 2021

Smad6 inhibits signalling by the TGF-beta superfamily

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7 January 2021

Bone morphogenetic protein-12 and -13 inhibit terminal differentiation of myoblasts, but do not induce their differentiation into osteoblasts

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7 January 2021

Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation

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7 January 2021

Heterodimeric bone morphogenetic proteins show enhanced activity in vitro and in vivo

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7 January 2021

Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity

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7 January 2021

Fibrodysplasia ossificans progressiva: a clue from the fly?

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7 January 2021

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage

1 reference

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7 January 2021

Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Immunohistochemical demonstration of bone morphogenetic protein-2 and transforming growth factor-beta in the ossification of the posterior longitudinal ligament of the cervical spine

1 reference

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7 January 2021

Bone morphogenetic protein-1: the type I procollagen C-proteinase

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

The role of BMPs and GDFs in development of region-specific skeletal structures

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF beta superfamily

1 reference

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7 January 2021

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

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7 January 2021

Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Restriction fragment length polymorphism of genes of the alpha 2(XI) collagen, bone morphogenetic protein-2, alkaline phosphatase, and tumor necrosis factor-alpha among patients with ossification of posterior longitudinal ligament and controls from

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Activin-binding protein is present in pituitary.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

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7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons

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7 January 2021

Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons

1 reference

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7 January 2021

Bone morphogenetic protein-2 but not bone morphogenetic protein-4 and -6 stimulates chemotactic migration of human osteoblasts, human marrow osteoblasts, and U2-OS cells

1 reference

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7 January 2021

Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs

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7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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7 January 2021

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning

1 reference

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7 January 2021

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development

1 reference

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7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

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7 January 2021

Osteogenic protein-1 (BMP-7) inhibits cell proliferation and stimulates the expression of markers characteristic of osteoblast phenotype in rat osteosarcoma (17/2.8) cells

1 reference

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7 January 2021

TGFbeta signaling: receptors, transducers, and Mad proteins.

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7 January 2021

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

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7 January 2021

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

1 reference

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7 January 2021

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation

1 reference

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7 January 2021

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

1 reference

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7 January 2021

Signal transduction via serine/threonine kinase receptors

1 reference

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7 January 2021

Activin-binding protein from rat ovary is follistatin.

1 reference

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7 January 2021

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

1 reference

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7 January 2021

Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing

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7 January 2021

The MAP kinase cascade is essential for diverse signal transduction pathways

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7 January 2021

Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5

1 reference

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7 January 2021

Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors

1 reference

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7 January 2021

Orthotopic ossification of the spinal ligaments of Zucker fatty rats: a possible animal model for ossification of the human posterior longitudinal ligament

1 reference

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7 January 2021

Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Chemotactic response of osteoblastlike cells to transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

The gene for bone morphogenetic protein 2A (BMP2A) is localized to human chromosome 20p12 by radioactive and nonradioactive in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Regulation of cartilage and bone differentiation by bone morphogenetic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone and cartilage differentiation

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7 January 2021

Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens.

1 reference

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7 January 2021

Association of diffuse idiopathic skeletal hyperostosis (DISH) and calcification and ossification of the posterior longitudinal ligament

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Mad-related genes in the human

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7 January 2021

Complete regeneration of bone in the baboon by recombinant human osteogenic protein-1 (hOP-1, bone morphogenetic protein-7).

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Signaling pathways in skeletal formation: a role for BMP receptors

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Cloning and characterization of a human type II receptor for bone morphogenetic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Genetic Study of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine with Human Leukocyte Antigen Haplotype

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Mesoderm induction by BMP-4 and -7 heterodimers

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

A human chondrodysplasia due to a mutation in a TGF-beta superfamily member

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Platelet-derived growth factor B chain homodimer enhances chemotaxis and DNA synthesis in normal osteoblast-like cells (MC3T3-E1).

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone: formation by autoinduction

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Human bone morphogenetic protein (hBMP)

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Localization of osteogenic protein-1 (bone morphogenetic protein-7) during human embryonic development: high affinity binding to basement membranes

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6)

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Purification and characterization of other distinct bone-inducing factors

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Recombinant human bone morphogenetic protein induces bone formation

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Novel regulators of bone formation: molecular clones and activities

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https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Mechanism of activation of the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Bone morphogenetic protein receptors

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Growth/Differentiation Factor-5 Induces Angiogenesisin Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Requirement for BMP signaling in interdigital apoptosis and scale formation.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2898%2900053-2

7 January 2021

10.1016/S8756-3282(98)00053-2

Identifiers

DOI

1 reference

7 February 2018

1 reference

7 February 2018