(Q47980783)

7 February 2018

review article

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title

Human antibodies by design. (English)

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7 February 2018

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Vaughan TJ

1

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7 February 2018

Osbourn JK

series ordinal

2

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7 February 2018

Tempest PR

series ordinal

3

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7 February 2018

publication date

1 June 1998

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7 February 2018

published in

Nature Biotechnology

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7 February 2018

volume

16

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7 February 2018

page(s)

535-539

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7 February 2018

issue

6

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7 February 2018

https://scigraph.springernature.com/pub.10.1038/nbt0698-535

exact match

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cites work

Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis

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Reshaping human antibodies for therapy

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Anatomy of the antibody molecule

21 January 2018

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Phage antibodies: filamentous phage displaying antibody variable domains

21 January 2018

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Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site

21 January 2018

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Affinity maturation of a high-affinity human monoclonal antibody against the third hypervariable loop of human immunodeficiency virus: use of phage display to improve affinity and broaden strain reactivity

21 January 2018

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CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

21 January 2018

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Pathfinder selection: in situ isolation of novel antibodies

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0698-535

Cloning of anti-Gal Fabs from combinatorial phage display libraries: structural analysis and comparison of Fab expression in pComb3H and pComb8 phage

21 January 2018

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Organ targeting in vivo using phage display peptide libraries

21 January 2018

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Designing and optimizing library selection strategies for generating high-affinity antibodies

21 January 2018

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Applications of DNA shuffling to pharmaceuticals and vaccines

21 January 2018

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Production of fully human antibodies by transgenic mice

21 January 2018

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Production of human antibody repertoires in transgenic mice

21 January 2018

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Antigen-specific human antibodies from mice comprising four distinct genetic modifications

21 January 2018

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Continuous cultures of fused cells secreting antibody of predefined specificity

21 January 2018

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7 January 2021

Therapeutic Human Antibodies Derived from PCR Amplification of B‐Cell Variable Regions

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Recombinant antibodies possessing novel effector functions

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Production of functional chimaeric mouse/human antibody

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Mouse/human chimeric monoclonal antibody in man: kinetics and immune response

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Replacing the complementarity-determining regions in a human antibody with those from a mouse

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Antibody framework residues affecting the conformation of the hypervariable loops

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

A humanized antibody that binds to the interleukin 2 receptor

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

A possible procedure for reducing the immunogenicity of antibody variable domains while preserving their ligand-binding properties

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7 January 2021

Humanization of murine monoclonal antibodies through variable domain resurfacing

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7 January 2021

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

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7 January 2021

Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection

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7 January 2021

CAMPATH-1H, a humanized monoclonal antibody, in refractory rheumatoid arthritis. An intravenous dose-escalation study

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Making antibodies by phage display technology

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https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Isolation of high affinity human antibodies directly from large synthetic repertoires.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Direct demonstration of MuSK involvement in acetylcholine receptor clustering through identification of agonist ScFv

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Cell selection strategies for making antibodies from variable gene libraries: trapping the memory pool

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Directing phage selections towards specific epitopes

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Isolation of human anti-red blood cell antibodies by repertoire cloning

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Human anti-self antibodies with high specificity from phage display libraries.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Selection of phage antibodies by binding affinity

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Strategies for expressing human antibody repertoires in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

A repertoire of monoclonal antibodies with human heavy chains from transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Assembly and extension of yeast artificial chromosomes to build up a large locus

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

By-passing immunization. Human antibodies from V-gene libraries displayed on phage

1 reference

https://api.crossref.org/works/10.1038%2FNBT0698-535

7 January 2021

Identifiers

DOI

10.1038/NBT0698-535

1 reference

7 February 2018

Dimensions Publication ID

1003509924

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Fatcat ID

release_lku74tr65bb5bf3schyil7mv2e

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PubMed ID

9624683

1 reference

7 February 2018