(Q48001894)

7 February 2018

title

1,3-Bis(2-chloroethyl)-1-nitrosourea as thiol-carbamoylating agent in biological systems (English)

1 reference

7 February 2018

15 1,3-Bis(2-chloroethyl)-1-nitrosourea as Thiol-carbamoylating agent in biological Systems (English)

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7651196

17 July 2024

author name string

K. Becker

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7651196

17 July 2024

R. H. Schirmer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7651196

17 July 2024

language of work or name

English

0 references

publication date

1 January 1995

1 reference

7 February 2018

published in

Methods in Enzymology

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7 February 2018

volume

251

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7 February 2018

page(s)

173-188

1 reference

7 February 2018

Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their chemotherapeutic potential

cites work

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1 reference

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Comparison of the properties of metabolites of CCNU

17 July 2024

4

1 reference

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Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates

17 July 2024

6

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. A crystallographic analysis

17 July 2024

7

1 reference

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Glutathione and N-acetylcysteine conjugates of 2-chloroethyl isocyanate. Identification as metabolites of N,N'-bis(2-chloroethyl)-N-nitrosourea in the rat and inhibitory properties toward glutathione reductase in vitro

17 July 2024

8

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Selective and irreversible inhibition of glutathione reductase in vitro by carbamate thioester conjugates of methyl isocyanate

17 July 2024

9

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Mechanism of glutathione-mediated DNA damage by the antineoplastic agent 1,3-bis(2-chloroethyl)-N-nitrosourea

17 July 2024

10

1 reference

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Active lung fibrosis up to 17 years after chemotherapy with carmustine (BCNU) in childhood

17 July 2024

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Redox processes in malaria and other parasitic diseases. Determination of intracellular glutathione

17 July 2024

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Flavins and flavoproteins

17 July 2024

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847

Becker

1991

1 reference

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Comparative study on the influence of two 2-chloroethylnitrosoureas with different carbamoylating potential towards glutathione and glutathione-related enzymes in different organs of the rat.

17 July 2024

17

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Glutathione reductase-deficient erythrocytes as host cells of malarial parasites

17 July 2024

18

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Oxidative stress as a defense mechanism against parasitic infections

17 July 2024

19

1 reference

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Folding of the four domains and dimerization are impaired by the Gly446-->Glu exchange in human glutathione reductase. Implications for the design of antiparasitic drugs

17 July 2024

20

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds

17 July 2024

23

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Protective role of the glutathione redox cycle against adriamycin-mediated toxicity in isolated hepatocytes

17 July 2024

25

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis

17 July 2024

26

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Enhanced in vitro cytotoxicity of 1,3-bis-(2-chloroethyl)-1-nitrosourea or buthionine sulfoximine combined with a reactive oxygen-generating enzyme immunotoxin

17 July 2024

27

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Antimalarial activity of the ethanol/alcohol oxidase system in vitro

17 July 2024

28

1 reference

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Effect of 7-hydroxymethyl-12-methylbenz[a]anthracene and 1,3-bis-(2-chloroethyl)-1-nitrosourea on enzyme activities and oxidation of glutathione in cultured rat adrenal cells

17 July 2024

29

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Oxidation of glutathione during hydroperoxide metabolism. A study using isolated hepatocytes and the glutathione reductase inhibitor 1,3-bis(2-chloroethyl)-1-nitrosourea

17 July 2024

30

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

17 July 2024

Tissue sulfhydryl groups

33

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Influence of glutathione on the mutagenicity of 2-chloroethylnitrosoureas. Mutagenic potential of glutathione derivatives formed from 2-chloroethylnitrosoureas and glutathione

17 July 2024

34

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Effect of carbamate thioester derivatives of methyl- and 2-chloroethyl isocyanate on glutathione levels and glutathione reductase activity in isolated rat hepatocytes

17 July 2024

35

1 reference

https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

Glutathione reductase from human erythrocytes. Isolation of the enzyme and sequence analysis of the redox-active peptide

17 July 2024

36

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https://api.crossref.org/works/10.1016/0076-6879(95)51120-2

17 July 2024

Identifiers

1 reference

7 February 2018

1 reference

7 February 2018