(Q48005418)

7 February 2018

review article

1 reference

title

Diversity of DNA topoisomerases I and inhibitors. (English)

1 reference

7 February 2018

author name string

Pommier Y

series ordinal

1

1 reference

7 February 2018

publication date

1 March 1998

1 reference

7 February 2018

published in

Biochimie

1 reference

7 February 2018

volume

80

1 reference

7 February 2018

page(s)

255-270

1 reference

7 February 2018

issue

3

1 reference

7 February 2018

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

1 reference

7 January 2021

Eukaryotic DNA topoisomerases I.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

1 reference

7 January 2021

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Recent studies of DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

1 reference

7 January 2021

DNA topoisomerase poisons as antitumor drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Partial purification of .omega. protein from calf thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

ATP-dependent DNA topoisonmerase from D. melanogaster reversibly catenates duplex DNA rings

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

DNA Topoisomerase I from Mitochondria of Xenopus laevis Oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Purification and characterization of a type I DNA topoisomerase from calf thymus mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Targeted disruption of the mouse topoisomerase I gene by camptothecin selection

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Conditional growth of Escherichia coli caused by expression of vaccinia virus DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Expression of the topoisomerase I gene in serum stimulated human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Using yeast to understand drugs that target topoisomerases.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Differential poisoning of human and Aspergillus nidulans DNA topoisomerase I by bi- and terbenzimidazoles

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Identification and DNA sequence of the Shope fibroma virus DNA topoisomerase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Partial transcriptional mapping of the fowlpox virus genome and analysis of the EcoRI L fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Genes of variola and vaccinia viruses necessary to overcome the host protective mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

SFV Topoisomerase: Sequence Specificity in a Genetically Mapped Interval

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Topoisomerase I activity associated with human immunodeficiency virus (HIV) particles and equine infectious anemia virus core.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Cellular topoisomerase I activity associated with HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Topoisomerase I and II activities are required for Epstein-Barr virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Role of DNA topoisomerase I in the replication of herpes simplex virus type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Reconstitution of human topoisomerase I by fragment complementation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The domain organization of human topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Biochemical and biophysical analyses of recombinant forms of human topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The current status of camptothecin analogues as antitumor agents

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

CPT-11 (irinotecan) in the treatment of colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue: 1996.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Current perspectives on camptothecins in cancer treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Specific cleavage of chicken alpha A-globin and human c-Ha-ras genes by two molecular forms of calf thymus topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Enrichment and depletion of Hela topoisomerase I recognition sites among specific types of DNA elements

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Gene mutation analysis and quantitation of DNA topoisomerase I in previously untreated non-small cell lung carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Inhibition of topoisomerase I by anthracycline antibiotics: evidence for general inhibition of topoisomerase I by DNA-binding agents

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Topoisomerase I gene expression and cell sensitivity to camptothecin in human cell lines of different tumor types.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Apoptosis induced by DNA topoisomerase I and II inhibitors in human leukemic HL-60 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Cell death induced by topoisomerase inhibitors. Role of calcium in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Exposure to camptothecin breaks leading and lagging strand simian virus 40 DNA replication forks

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

A model for topoisomerase I-mediated insertions and deletions with duplex DNA substrates containing branches, nicks, and gaps

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

DNA recombinase activity of eukaryotic DNA topoisomerase I; effects of camptothecin and other inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Camptothecin hypersensitivity in poly(adenosine diphosphate-ribose) polymerase-deficient cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Secondary leukemia associated with a conventional dose of etoposide: review of serial germ cell tumor protocols

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Infant leukemia, topoisomerase II inhibitors, and the MLL gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

UCE6, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from actinomycetes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

UCE1022, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from Paecilomyces

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Correlation between the formation of cleavable complex with topoisomerase I and growth-inhibitory activity for saintopin-type antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Inhibitors of DNA topoisomerase I isolated from the roots of Zanthoxylum nitidum

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Inhibition of topoisomerase I function by nitidine and fagaronine

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Synthesis and evaluation of new 6-amino- substituted benzo[c]phenanthridine derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Experimental antileukemic agents. Coralyne, analogs, and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Inhibition of topoisomerase I function by coralyne and 5,6-dihydrocoralyne

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Inhibitors of DNA topoisomerase I and II isolated from the Coptis rhizomes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Molecular Interactions of DNA-Topoisomerase I and II Inhibitor with DNA and Topoisomerases and in Ternary Complexes: Binding Modes and Biological Effects for Intoplicine Derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Phase I and pharmacology study of intoplicine (RP 60475; NSC 645008), novel topoisomerase I and II inhibitor, in cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Structure-mutagenicity relationships in series of 11H-indolo[3,2-c]quinoline-1,4-diones, tetrahydro-11H-indolo[3,2-c]quinoline-1,4-diones and 11H-pyrido[3',4':4,5]pyrrolo[3,2-c]quinoline-1,4-diones with leukemia cytotoxic properties. Relations with

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Differences in the topoisomerase I cleavage complexes formed by camptothecin and wakayin, a DNA-intercalating marine natural product

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

UCT-4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from streptomyces sp.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Induction of a Common Pathway of Apoptosis by Staurosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Structure-activity relationships in a series of substituted indolocarbazoles: topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Synthesis and evaluation of terbenzimidazoles as topoisomerase I inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Structure-activity relationships of benzimidazoles and related heterocycles as topoisomerase I poisons

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Antagonistic effect of aclarubicin on camptothecin induced cytotoxicity: role of topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Development of anthracenyl-amino acid conjugates as topoisomerase I and II inhibitors that circumvent drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Cell cycle effects of the novel topoisomerase I inhibitor NU/ICRF 505 in a panel of Chinese hamster ovary cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Molecular modeling of the interaction of anthracenyl-amino acid topoisomerase inhibitors with the DNA sequence d(CGTACG)

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

New naphthacenecarboxamide antibiotics, TAN-1518 A and B, have inhibitory activity against mammalian DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Distamycin inhibition of topoisomerase I-DNA interaction: a mechanistic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Bisindolylmaleimides linked to DNA minor groove binding lexitropsins: synthesis, inhibitory activity against topoisomerase I, and biological evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

beta-Lapachone, an inhibitor of oncornavirus reverse transcriptase and eukaryotic DNA polymerase-alpha. Inhibitory effect, thiol dependence and specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

A strategy for identifying novel, mechanistically unique inhibitors of topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

Naturally occurring inhibitors of topoisomerase I mediated DNA relaxation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

TAN-1496 A, C and E, diketopiperazine antibiotics with inhibitory activity against mammalian DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2898%2980008-4

7 January 2021

10.1016/S0300-9084(98)80008-4

Identifiers

DOI

1 reference

7 February 2018

PubMed ID

9615865

1 reference

7 February 2018