(Q48005750)

7 February 2018

http://europepmc.org/abstract/MED/28053050

title

Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons (English)

1 reference

7 February 2018

http://europepmc.org/abstract/MED/28053050

1 reference

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

Nathalie Bernard-Marissal

9 June 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Darren J Moore

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Graham Knott

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Lu Zheng

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Norman Moullan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Davide D'Amico

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Patrick Aebischer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Johan Auwerx

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

4 January 2017

1 reference

7 February 2018

http://europepmc.org/abstract/MED/28053050

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

582-598

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

Living on the edge with too many mouths to feed: why dopamine neurons die.

9 June 2020

cites work

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21 January 2018

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A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

21 January 2018

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Parkin mutations are frequent in patients with isolated early-onset parkinsonism

21 January 2018

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The role of parkin in familial and sporadic Parkinson's disease

21 January 2018

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PINK1- and Parkin-mediated mitophagy at a glance

21 January 2018

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

21 January 2018

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A polyubiquitin chain reaction: parkin recruitment to damaged mitochondria

21 January 2018

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Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering

21 January 2018

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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria

21 January 2018

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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

21 January 2018

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Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons

21 January 2018

1 reference

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Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.

21 January 2018

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Quality control in mitochondria: use it, break it, fix it, trash it

21 January 2018

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Pharmacological approaches to restore mitochondrial function

21 January 2018

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The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

21 January 2018

1 reference

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Parkin: a multifaceted ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

21 January 2018

1 reference

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Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

The PINK1/Parkin pathway regulates mitochondrial morphology

21 January 2018

1 reference

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The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

21 January 2018

1 reference

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PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease

21 January 2018

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PPARγ and PGC-1α as therapeutic targets in Parkinson's

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Oxidative stress induces degradation of mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise

21 January 2018

1 reference

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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

21 January 2018

1 reference

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VDAC: the channel at the interface between mitochondria and the cytosol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes

21 January 2018

1 reference

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MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons

21 January 2018

1 reference

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Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease

21 January 2018

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The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease

21 January 2018

1 reference

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Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Endoplasmic reticulum-mitochondria contacts: function of the junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Parkin enhances mitochondrial biogenesis in proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

PINK1 and Parkin control localized translation of respiratory chain component mRNAs on mitochondria outer membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

21 January 2018

1 reference

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Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

1 reference

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Tissue- and cell-specific mitochondrial defect in Parkin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo

21 January 2018

1 reference

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Mitochondrial protein quality control: the mechanisms guarding mitochondrial health

21 January 2018

1 reference

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Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

21 January 2018

1 reference

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Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Regulation of DNA repair by parkin.

21 January 2018

1 reference

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Parkin in the regulation of fat uptake and mitochondrial biology: emerging links in the pathophysiology of Parkinson's disease

21 January 2018

1 reference

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Parkin-deficient mice are not a robust model of parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

Measuring In Vivo Mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW418

21 January 2018

Identifiers

DOI

10.1093/HMG/DDW418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28053050%20AND%20SRC:MED&resulttype=core&format=json

release_odp6g44bojfonk5v7ouydxrm3y

9 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/odp6g44bojfonk5v7ouydxrm3y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference