(Q48014886)

7 February 2018

review article

1 reference

title

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases. (English)

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7 February 2018

main subject

endoplasmic reticulum

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author name string

Treiman M

series ordinal

1

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7 February 2018

Caspersen C

series ordinal

2

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7 February 2018

Christensen SB

series ordinal

3

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7 February 2018

publication date

1 April 1998

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7 February 2018

Trends in Pharmacological Sciences

published in

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7 February 2018

volume

19

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7 February 2018

page(s)

131-135

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7 February 2018

issue

4

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7 February 2018

Molecular and cellular physiology of intracellular calcium stores

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1 reference

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7 January 2021

The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

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7 January 2021

Thapsigargin, a high affinity and global inhibitor of intracellular Ca2+ transport ATPases

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7 January 2021

Pharmacological tools for perturbing intracellular calcium storage

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7 January 2021

Purkinje neurons express the SERCA3 isoform of the organellar type Ca(2+)-transport ATPase.

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7 January 2021

The endoplasmic reticulum in PC12 cells. Evidence for a mosaic of domains differently specialized in Ca2+ handling

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7 January 2021

Binding of sesquiterpene lactone inhibitors to the Ca(2+)-ATPase

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7 January 2021

Kinetics of thapsigargin-Ca(2+)-ATPase (sarcoplasmic reticulum) interaction reveals a two-step binding mechanism and picomolar inhibition

1 reference

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7 January 2021

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

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7 January 2021

Derivatives of thapsigargin as probes of its binding site on endoplasmic reticulum Ca2+ ATPase. Stereoselectivity and important functional groups

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7 January 2021

Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain.

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7 January 2021

Characterization of the inositol trisphosphate-sensitive and insensitive calcium stores by selective inhibition of the endoplasmic reticulum-type calcium pump isoforms in isolated platelet membrane vesicles.

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7 January 2021

The Ca(2+)-ATPase isoforms of platelets are located in distinct functional Ca2+ pools and are uncoupled by a mechanism different from that of skeletal muscle Ca(2+)-ATPase

1 reference

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7 January 2021

Thapsigargin-resistant intracellular calcium pumps. Role in calcium pool function and growth of thapsigargin-resistant cells

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7 January 2021

Internal Ca2+ mobilization and secretion in bovine adrenal chromaffin cells

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7 January 2021

Mobilization of Ca2+ by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone in permeabilized insulin-secreting RINm5F cells: evidence for separate uptake and release compartments in inositol 1,4,5-trisphosphate-sensitive Ca2+ pool

1 reference

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7 January 2021

Intracellular Ca2+ signals activate apoptosis in thymocytes: studies using the Ca(2+)-ATPase inhibitor thapsigargin

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7 January 2021

Direct involvement of intracellular Ca2+ transport ATPase in the development of thapsigargin resistance by Chinese hamster lung fibroblasts.

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7 January 2021

Thapsigargin discriminates strongly between Ca(2+)-ATPase phosphorylated intermediates with different subcellular distributions in bovine adrenal chromaffin cells

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7 January 2021

Two classes of agonist-sensitive Ca2+ stores in platelets, as identified by their differential sensitivity to 2,5-di-(tert-butyl)-1,4-benzohydroquinone and thapsigargin

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7 January 2021

Human platelets express the SERCA2-b isoform of Ca(2+)-transport ATPase

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7 January 2021

Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone

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7 January 2021

Functional identification and quantitation of three intracellular calcium pools in GH4C1 cells: evidence that the caffeine-responsive pool is coupled to a thapsigargin-resistant, ATP-dependent process

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7 January 2021

Inhibition of L-type calcium-channel activity by thapsigargin and 2,5-t-butylhydroquinone, but not by cyclopiazonic acid

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7 January 2021

Thapsigargin-sensitive Ca(2+)-ATPases account for Ca2+ uptake to inositol 1,4,5-trisphosphate-sensitive and caffeine-sensitive Ca2+ stores in adrenal chromaffin cells

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7 January 2021

Phosphorylation of the Sarcoplasmic Reticulum and Sarcolemma

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7 January 2021

1 reference

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7 January 2021

The vmax of the Ca2+-ATPase of cardiac sarcoplasmic reticulum (SERCA2a) is not altered by Ca2+/calmodulin-dependent phosphorylation or by interaction with phospholamban

1 reference

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7 January 2021

Capacitative calcium entry

1 reference

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7 January 2021

Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2898%2901184-5

7 January 2021

Bcl-2 acts subsequent to and independent of Ca2+ fluxes to inhibit apoptosis in thapsigargin- and glucocorticoid-treated mouse lymphoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2898%2901184-5

7 January 2021

10.1016/S0165-6147(98)01184-5

Identifiers

DOI

1 reference

7 February 2018

PubMed ID

9612087

1 reference

7 February 2018