(Q48030138)

7 February 2018

title

Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin (English)

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7 February 2018

author name string

Mohamed Hussein

1

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7 February 2018

Martina Bettio

2

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7 February 2018

Anton Schmitz

3

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7 February 2018

Jeffrey S Hannam

4

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7 February 2018

Julian Theis

5

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7 February 2018

Günter Mayer

6

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7 February 2018

Stefan Dosa

7

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7 February 2018

Michael Gütschow

8

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7 February 2018

Michael Famulok

9

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7 February 2018

language of work or name

English

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publication date

10 July 2013

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7 February 2018

Angewandte Chemie International Edition

published in

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volume

52

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7 February 2018

issue

36

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7 February 2018

page(s)

9529-9533

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7 February 2018

Guanine nucleotide exchange factors of the cytohesin family and their roles in signal transduction

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1 reference

https://api.crossref.org/works/10.1002%2FANIE.201302207

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ARF family G proteins and their regulators: roles in membrane transport, development and disease.

21 January 2018

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The cytohesin Steppke is essential for insulin signalling in Drosophila

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Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance

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The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling

21 January 2018

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Cytohesins are cytoplasmic ErbB receptor activators

21 January 2018

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Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells

21 January 2018

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Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.

21 January 2018

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Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization

21 January 2018

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Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors

21 January 2018

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The aminobarbituric acid-hydantoin rearrangement

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Aptamer displacement identifies alternative small-molecule target sites that escape viral resistance

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A RNA-based approach towards small-molecule inhibitors.

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Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility

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SMART 5: domains in the context of genomes and networks

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Signal-dependent membrane targeting by pleckstrin homology (PH) domains

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Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains

21 January 2018

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Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains

21 January 2018

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Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

21 January 2018

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Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions

21 January 2018

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Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains

21 January 2018

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Inhibition of cell migration by PITENINs: the role of ARF6.

21 January 2018

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The resurgence of covalent drugs

21 January 2018

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Reversible covalent inhibition of a protein target.

21 January 2018

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Developing irreversible inhibitors of the protein kinase cysteinome

21 January 2018

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Targeting multifunctional proteins by virtual screening: structurally diverse cytohesin inhibitors with differentiated biological functions

21 January 2018

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A homogeneous fluorescence resonance energy transfer system for monitoring the activation of a protein switch in real time

21 January 2018

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Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANIE.201302207

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7 February 2018

release_w5jjwmwzybbqvfrxpxef3fogea

Fatcat ID

0 references

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7 February 2018