(Q48049044)

English

Simvastatin Therapy in the Acute Stage of Traumatic Brain Injury Attenuates Brain Trauma-Induced Depression-Like Behavior in Rats by Reducing Neuroinflammation in the Hippocampus

scientific article published on 12 July 2016

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Simvastatin Therapy in the Acute Stage of Traumatic Brain Injury Attenuates Brain Trauma-Induced Depression-Like Behavior in Rats by Reducing Neuroinflammation in the Hippocampus (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

0 references

1 reference

based on heuristic

inferred from title

author name string

Sher-Wei Lim

1

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Yow-Ling Shiue

2

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Jen-Chieh Liao

3

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Hsiao-Yue Wee

4

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Che-Chuan Wang

5

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Chung-Ching Chio

6

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Chin-Hung Chang

7

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Chiao-Ya Hu

8

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Jinn-Rung Kuo

9

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

publication date

12 July 2016

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

Neurocritical Care

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

26

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

1

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

122-132

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

https://scigraph.springernature.com/pub.10.1007/s12028-016-0290-6

0 references

Emotion circuits in the brain

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Prevalence of long-term disability from traumatic brain injury in the civilian population of the United States, 2005.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Treatment of depression following traumatic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Neuronal injury and loss after traumatic brain injury: time course and regional variability

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21 January 2018

Cytokines and acute neurodegeneration

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21 January 2018

Therapeutic evaluation of etanercept in a model of traumatic brain injury

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21 January 2018

Inflammatory response in acute traumatic brain injury: a double-edged sword

1 reference

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21 January 2018

Astrogliosis in CNS pathologies: is there a role for microglia?

1 reference

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21 January 2018

Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression

1 reference

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21 January 2018

Depressive-like behavior induced by tumor necrosis factor-α in mice.

1 reference

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21 January 2018

Tumor necrosis factor signaling.

1 reference

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21 January 2018

Use of statins in CNS disorders

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21 January 2018

Rho GTPases, statins, and nitric oxide

1 reference

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21 January 2018

Prophylactic but not delayed administration of simvastatin protects against long-lasting cognitive and morphological consequences of neonatal hypoxic-ischemic brain injury, reduces interleukin-1beta and tumor necrosis factor-alpha mRNA induction, an

1 reference

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21 January 2018

Lovastatin improves histological and functional outcomes and reduces inflammation after experimental traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Effects of statins on microglia

1 reference

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21 January 2018

Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

1 reference

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21 January 2018

Clinical pharmacokinetics and practical applications of simvastatin

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Effects of secretome obtained from normoxia-preconditioned human mesenchymal stem cells in traumatic brain injury rats

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Comparison of behavioral deficits and acute neuronal degeneration in rat lateral fluid percussion and weight-drop brain injury models

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Post-traumatic seizures exacerbate histopathological damage after fluid-percussion brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Extracellular signal-regulated kinase 1/2 is involved in a tamoxifen neuroprotective effect in a lateral fluid percussion injury rat model.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Resuscitation from experimental traumatic brain injury by magnolol therapy.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Is the forced swimming test a suitable model for revealing antidepressant activity?

1 reference

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21 January 2018

Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Microglial activation as a compelling target for treating acute traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Simvastatin reduces secondary brain injury caused by cortical contusion in rats: possible involvement of TLR4/NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Effect of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Combination therapy with fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, and simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, on experimental traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Simvastatin causes changes in affective processes in elderly volunteers

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Hyperlipidemia, statin use and the risk of developing depression: a nationwide retrospective cohort study.

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21 January 2018

Depressive symptoms and serum lipid levels in young adult women

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21 January 2018

Gender and genotype modulation of the association between lipid levels and depressive symptomatology in community-dwelling elderly (the ESPRIT study).

1 reference

https://api.crossref.org/works/10.1007%2FS12028-016-0290-6

21 January 2018

Temporal and spatial characterization of neuronal injury following lateral fluid-percussion brain injury in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins in acute brain injury: getting the cart before the horse

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NeuN, a neuronal specific nuclear protein in vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin attenuates the cerebral vascular endothelial inflammatory response in a rat traumatic brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and widespread microglial activation induced by traumatic brain injury in rat brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/27406816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12028-016-0290-6

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/27406816

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