(Q48063321)

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A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression

scientific article published on 23 February 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

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A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

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bipolar disorder

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based on heuristic

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author name string

D R Goldsmith

1

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

M H Rapaport

2

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

B J Miller

3

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

language of work or name

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publication date

23 February 2016

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

Molecular Psychiatry

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

21

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

12

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

1696-1709

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

https://scigraph.springernature.com/pub.10.1038/mp.2016.3

0 references

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

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Biological insights from 108 schizophrenia-associated genetic loci

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The immunology of bipolar disorder

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A systematic, quantitative review of blood autoantibodies in schizophrenia

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Evidence for a dysregulated immune system in the etiology of psychiatric disorders

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Meta-analysis of lymphocytes in schizophrenia: clinical status and antipsychotic effects

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Immunology of major depression

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Meta-analysis of the association between N-methyl-d-aspartate receptor antibodies and schizophrenia, schizoaffective disorder, bipolar disorder, and major depressive disorder.

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Taking the fuel out of the fire: evidence for the use of anti-inflammatory agents in the treatment of bipolar disorders.

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Effect of anti-inflammatory treatment on depression, depressive symptoms, and adverse effects: a systematic review and meta-analysis of randomized clinical trials

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Adjunctive use of nonsteroidal anti-inflammatory drugs for schizophrenia: a meta-analytic investigation of randomized controlled trials

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Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update

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A meta-analysis of cytokines in major depression

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Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects

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Cytokines in bipolar disorder: a systematic review and meta-analysis

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Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review

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Cytokine function in medication-naive first episode psychosis: a systematic review and meta-analysis

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Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

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Elevated serum level of type-2 cytokine and low IL-17 in first episode psychosis and schizophrenia in relapse.

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Antipsychotics can modulate the cytokine profile in schizophrenia: attenuation of the type-2 inflammatory response

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Inflammation in patients with schizophrenia: the therapeutic benefits of risperidone plus add-on dextromethorphan

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Interleukin-12 plasma levels in drug-naïve patients with a first episode of psychosis: effects of antipsychotic drugs

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Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment

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Activation of Th17 cells in drug naïve, first episode schizophrenia.

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Serum and gene expression profile of cytokines in first-episode psychosis

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An activated set point of T-cell and monocyte inflammatory networks in recent-onset schizophrenia patients involves both pro- and anti-inflammatory forces.

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Increased Interleukin-17 and decreased BAFF serum levels in drug-free acute schizophrenia

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Metabolic profile of antipsychotic-naive individuals with non-affective psychosis

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Abnormalities in serum concentrations of interleukin-2, interferon-alpha and interferon-gamma in schizophrenia not detected

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Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosis.

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Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naïve schizophrenia: evidence for differential susceptibility?

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Effect of risperidone on serum cytokines

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Th1, Th2 and Th3 cytokine alteration in schizophrenia

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Cytokine changes and tryptophan metabolites in medication-naïve and medication-free schizophrenic patients.

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Lower plasma CC16, a natural anti-inflammatory protein, and increased plasma interleukin-1 receptor antagonist in schizophrenia: effects of antipsychotic drugs

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Increased tumor necrosis factor-alpha concentrations with interleukin-4 concentrations in exacerbations of schizophrenia.

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Antipsychotic treatment may alter T-helper (TH) 2 arm cytokines.

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Serum-soluble interleukin-2 receptors in neuroleptic-naive schizophrenic subjects and in medicated schizophrenic subjects with and without tardive dyskinesia

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Autoantibodies against 60-kDa heat shock protein in schizophrenia

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Effect of neuroleptic administration on serum levels of soluble IL-2 receptor-alpha and IL-1 receptor antagonist in schizophrenic patients.

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The interaction of nuclear factor-kappa B and cytokines is associated with schizophrenia

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Elevated levels of adiponectin and other cytokines in drug naïve, first episode schizophrenia patients with normal weight

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Changes in pro-inflammatory cytokines and body weight during 6-month risperidone treatment in drug naïve, first-episode schizophrenia

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Decreased interleukin-10 serum levels in first-episode drug-naïve schizophrenia: relationship to psychopathology.

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Elevated interleukin-18 serum levels in chronic schizophrenia: Association with psychopathology.

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Interleukin 18 and cognitive impairment in first episode and drug naïve schizophrenia versus healthy controls

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Peripheral biomarkers and illness activity in bipolar disorder

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IL-23 and TGF-β1 levels as potential predictive biomarkers in treatment of bipolar I disorder with acute manic episode.

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Immunologic variables in acute mania of bipolar disorder

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Elevated levels of IL-6 and IL-18 in manic and hypomanic states in rapid cycling bipolar disorder patients.

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Cytokine profiles in bipolar affective disorder: focus on acutely ill patients.

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Plasma levels of soluble transferrin receptors and Clara cell protein (CC16) during bipolar mania and subsequent remission.

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IL-6 levels decrease with SSRI treatment in patients with major depression.

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Investigation of circulating endothelial progenitor cells and angiogenic and inflammatory cytokines during recovery from an episode of major depression.

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Pro-inflammatory cytokines and treatment response to escitalopram in major depressive disorder

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Might different cytokine trends in depressed patients receiving duloxetine indicate differential biological backgrounds.

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Variations in circulating cytokine levels during 52 week course of treatment with SSRI for major depressive disorder

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T-helper 1/T-helper 2 cytokine imbalance and clinical phenotypes of acute-phase major depression.

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Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression

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Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression.

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Indicators of immune activation in major depression

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Brain-derived neurotrophic factor, adiponectin, and proinflammatory markers in various subtypes of depression in young men.

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Pro- and anti-inflammatory cytokine balance in major depression: effect of sertraline therapy

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Inflammation and schizophrenia: alterations in cytokine levels and perturbation in antioxidative defense systems.

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Peripheral interleukin-2 level is associated with negative symptoms and cognitive performance in schizophrenia.

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Kynurenine pathway in psychosis: evidence of increased tryptophan degradation.

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Persistently increased serum soluble interleukin-2 receptors in continuously ill patients with schizophrenia

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Is T-helper type 2 shift schizophrenia-specific? Primary results from a comparison of related psychiatric disorders and healthy controls.

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Increased annexin-V and decreased TNF-α serum levels in chronic-medicated patients with schizophrenia.

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Lifestyle modification and behavior therapy effectively reduce body weight and increase serum level of brain-derived neurotrophic factor in obese non-diabetic patients with schizophrenia

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Association of plasma IL-6 and soluble IL-6 receptor levels with the Asp358Ala polymorphism of the IL-6 receptor gene in schizophrenic patients.

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Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder.

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Inflammation in psychotic disorders: a population-based study.

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Circulating levels of sTNFR1 as a marker of severe clinical course in schizophrenia.

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Comparison of inflammatory cytokine levels among type I/type II and manic/hypomanic/euthymic/depressive states of bipolar disorder

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Increased levels of adipokines in bipolar disorder.

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Altered intracellular signaling cascades in peripheral blood mononuclear cells from BD patients.

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Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder

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Plasma concentrations of soluble cytokine receptors in euthymic bipolar patients with and without subsyndromal symptoms

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Levels of TNF-α, soluble TNF receptors (sTNFR1, sTNFR2), and cognition in bipolar disorder.

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Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia

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Association of thalamic serotonin transporter and interleukin-10 in bipolar I disorder: a SPECT study

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The relationship between interleukin-1 receptor antagonist and cognitive function in older adults with bipolar disorder

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Interleukin-1β is associated with depressive episode in major depression but not in bipolar disorder.

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Immune parameters in euthymic bipolar patients and normal volunteers

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Selected cytokine profiles during remission in bipolar patients.

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Association between erythrocyte n-3 polyunsaturated fatty acids and biomarkers of inflammation and oxidative stress in patients with and without depression.

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Interleukin-1beta serum levels is increased in antidepressant-free elderly depressed patients.

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Circulating cytokine concentrations are not associated with major depressive disorder in a community-based cohort

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Inflammatory markers and sleep disturbance in major depression

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Th2 cytokine response in Major Depressive Disorder patients before treatment.

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Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder

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A detailed examination of cytokine abnormalities in Major Depressive Disorder

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Bias in meta-analysis detected by a simple, graphical test

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The TRAF6-NF kappa B signaling pathway in autoimmunity: not just inflammation.

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Lower subjective social status exaggerates interleukin-6 responses to a laboratory stressor

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The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature

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Increased serum interleukin-8 and interleukin-10 in schizophrenic patients resistant to treatment with neuroleptics and the stimulatory effects of clozapine on serum leukemia inhibitory factor receptor

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Serum levels of interleukin-6 and tumor necrosis factor-alpha in exacerbation and remission phase of schizophrenia.

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Increased interleukin-6 and tumor necrosis factor alpha in first episode schizophrenia patients versus healthy controls

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

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Acute phase proteins in major depression

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Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma levels of interleukin-6, interleukin-10, and interleukin-1 receptor antagonist in depression: comparison between the acute state and after remission

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https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased serum interleukin 2 receptor concentration in schizophrenic and brain-damaged subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with schizophrenia show raised serum levels of the pro-inflammatory chemokine CCL2: association with the metabolic syndrome in patients?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroleptic treatment increases soluble IL-2 receptors and decreases soluble IL-6 receptors in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum interleukin-6 concentration in schizophrenia: elevation associated with duration of illness

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-helper types 1, 2, and 3 cytokine interactions in symptomatic manic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased interleukin-6 level in Taiwanese schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plasma levels of interleukin-12 in schizophrenia, major depression and bipolar mania: effects of psychotropic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of interleukin-1beta, interleukin-6, soluble interleukin-2 receptor and tumor necrosis factor alpha of depressed patients in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of symptomatic severity on elevation of plasma soluble interleukin-2 receptor in bipolar mania

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between interleukins, neurotransmitters and psychopathology in drug-free male schizophrenics

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased serum levels of interleukin-2 and interleukin-6 in Indian Bengalee schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum levels of soluble IL-2 receptor alpha, IL-6 and IL-1 receptor antagonist in schizophrenia before and during neuroleptic administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of IL-12 and TGF-beta1 in the pathophysiology of major depressive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine serum levels, autologous mixed lymphocyte reaction and surface marker analysis in never medicated and chronically medicated schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of indices of cell-mediated immunity in bipolar mania

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory markers and their relationships with leptin and insulin from acute mania to full remission in bipolar disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of serum cytokine levels and cytokine production in whole blood cultures of paranoid schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine levels in euthymic bipolar patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/26903267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MP.2016.3

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/26903267

ResearchGate publication ID

0 references

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