(Q48067523)

8 February 2018

title

Alterations of the p53, Rb and MDM2 genes in osteosarcoma (English)

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8 February 2018

author name string

C W Miller

1

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8 February 2018

A Aslo

2

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8 February 2018

A Won

3

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8 February 2018

M Tan

4

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8 February 2018

B Lampkin

5

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8 February 2018

H P Koeffler

6

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8 February 2018

publication date

1 January 1996

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8 February 2018

Journal of Cancer Research and Clinical Oncology

published in

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8 February 2018

volume

122

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8 February 2018

issue

9

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8 February 2018

page(s)

559-565

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8 February 2018

https://scigraph.springernature.com/pub.10.1007/bf01213553

exact match

0 references

cites work

Structural alterations of the RB1 gene in human soft tissue tumours

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Complete association of loss of heterozygosity of chromosomes 13 and 17 in osteosarcoma

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Allelotype analysis in osteosarcomas: frequent allele loss on 3q, 13q, 17p, and 18q.

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Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

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p53 abnormalities in different subtypes of human sarcomas

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Amplification of a gene encoding a p53-associated protein in human sarcomas

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Interaction of adenoviral proteins with pRB and p53.

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Germ-line and somatic p53 gene mutations in multifocal osteogenic sarcoma

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MDM2 gene amplification in metastatic osteosarcoma

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T antigen is bound to a host protein in SY40-transformed cells

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Relationship of p53 to the control of apoptotic cell death

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Mutation spectrum of the retinoblastoma gene in osteosarcomas

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Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2

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Rearrangement of the p53 gene in human osteogenic sarcomas

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Assignment of common allele loss in osteosarcoma to the subregion 17p13

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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Mutations in the p53 gene occur in diverse human tumour types

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Alterations of retinoblastoma susceptible gene accompanied by c-myc amplification in human bone and soft tissue tumors

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p53 gene mutations and abnormal retinoblastoma protein in radiation-induced human sarcomas

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N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis

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Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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Mutation spectrum of the p53 gene in bone and soft tissue sarcomas

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Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene.

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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Identification and characterization of a p53 gene mutation in a human osteosarcoma cell line

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Studies of the RB1 gene and the p53 gene in human osteosarcomas

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Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma

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Involvement of the retinoblastoma gene in primary osteosarcomas and other bone and soft-tissue tumors

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Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.

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Polymorphism at codon 213 within the p53 gene

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Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE)

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Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas

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Detection of loss of heterozygosity in tumor DNA samples by PCR

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12 December 2020

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

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Studies of the retinoblastoma gene in human sarcomas

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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12 December 2020

Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (pp110RB) in osteosarcomas and synovial sarcomas

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Frequency and structure of p53 rearrangements in human osteosarcoma

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12 December 2020

Identifiers

DOI

10.1007/BF01213553

1 reference

8 February 2018

1 reference

8 February 2018