(Q48091937)

8 February 2018

title

Recent advances in retrometabolic design approaches (English)

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8 February 2018

author name string

Bodor N

series ordinal

1

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8 February 2018

language of work or name

English

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publication date

1 November 1999

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8 February 2018

Journal of Controlled Release

published in

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8 February 2018

volume

62

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8 February 2018

issue

1-2

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8 February 2018

page(s)

209-222

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8 February 2018

Drug targeting via retrometabolic approaches

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Computer-assisted design of new drugs based on retrometabolic concepts.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Ocular absorption and distribution of loteprednol etabonate, a soft steroid, in rabbit eyes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Metabolism, distribution, and transdermal permeation of a soft corticosteroid, loteprednol etabonate

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Safety and efficacy of loteprednol etabonate for treatment of papillae in contact lens-associated giant papillary conjunctivitis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Loteprednol etabonate: comparison with other steroids in two models of intraocular inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

A controlled evaluation of the efficacy and safety of loteprednol etabonate in the prophylactic treatment of seasonal allergic conjunctivitis. Loteprednol Allergic Conjunctivitis Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. The Loteprednol Etabonate Giant Papillary Conjunctivitis Study Group I

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Failure to detect systemic levels, and effects of loteprednol etabonate and its metabolite, PJ-91, following chronic ocular administration

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Designing safer drugs based on the soft drug approach

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Soft drugs: principles and methods for the design of safe drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

A comparison of intraocular pressure elevating activity of loteprednol etabonate and dexamethasone in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Soft drugs. 18. Oral and rectal delivery of loteprednol etabonate, a novel soft corticosteroid, in rats--for safer treatment of gastrointestinal inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Soft drugs. 19. Pharmacokinetics, metabolism and excretion of a novel soft corticosteroid, loteprednol etabonate, in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Site-specific, sustained release of drugs to the brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved delivery through biological membranes. 11. A redox chemical drug-delivery system and its use for brain-specific delivery of phenylethylamine

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved delivery through biological membranes XIV: Brain-specific, sustained delivery of testosterone using a redox chemical delivery system

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved Delivery Through Biological Membranes. XXIV. Synthesis, in Vitro Studies, and in Vivo Characterization of Brain-Specific and Sustained Progestin Delivery Systems

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Evidence for prolonged suppression of stress-induced release of adrenocorticotropic hormone and corticosterone with a brain-enhanced dexamethasone-redox delivery system

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Effect of a chemical delivery system for dexamethasone (Dex-CDS) on peritumoral edema in an experimental brain tumor model

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Extension of a redox-based chemical delivery system to alpha, beta-unsaturated ketones

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved delivery through biological membranes. 32. Synthesis and biological activity of brain-targeted delivery systems for various estradiol derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

17 beta-estradiol attenuates fimbrial lesion-induced decline of ChAT-immunoreactive neurons in the rat medial septum

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Brain-specific chemical delivery systems for beta-lactam antibiotics. Synthesis and properties of some dihydropyridine and dihydroiosquinoline derivatives of benzylpenicillin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Potential treatment of herpes simplex virus encephalitis by brain-specific delivery of trifluorothymidine using a dihydropyridine in equilibrium pyridinium salt type redox delivery system

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Brain, Blood, and Cerebrospinal Fluid Distribution of a Zidovudine Chemical Delivery System in Rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Evaluation of a brain-targeting zidovudine chemical delivery system in dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become 'locked' in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

A pro-drug of zidovudine with enhanced efficacy against human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Synthesis and biological evaluation of prodrugs of zidovudine

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Comparative pharmacokinetics of two prodrugs of zidovudine in rabbits: enhanced levels of zidovudine in brain tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Hybrid pharmacokinetic models to describe anti-HIV nucleoside brain disposition following parent and prodrug administration in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

A dihydropyridine carrier system for sustained delivery of 2',3'-dideoxynucleosides to the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Enhanced delivery of ganciclovir to the brain through the use of redox targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systems

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Redox delivery system for brain-specific, sustained release of dopamine.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Synthesis and evaluation of a redox chemical delivery system for brain-enhanced dopamine containing an activated carbamate-type ester

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Anxiolytic activity of a brain delivery system for GABA.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Synthesis and evaluation of brain-targeted chemical delivery systems for the neurotrophomodulator 4-methylcatechol

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved anticonvulsant activity of phenytoin by a redox brain delivery system. III: Brain uptake and pharmacological effects

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

In vitro and in vivo investigations of dihydropyridine-based chemical delivery systems for anticonvulsants

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Synthesis, biological evaluation, calcium channel antagonist activity, and anticonvulsant activity of felodipine coupled to a dihydropyridine-pyridinium salt redox chemical delivery system.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Redox derivatives of tranylcypromine: syntheses, properties, and monoamine oxidase inhibitor activity of some chemical delivery systems

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Application of a brain-targeting chemical delivery system to 9-amino-1,2,3,4-tetrahydroacridine.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Improved delivery through biological membranes. XXXVII. Synthesis and stability of novel redox derivatives of naproxen and indomethacin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Antihypertensive activity of redox derivatives of tryptophan.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

A strategy for delivering peptides into the central nervous system by sequential metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

Octanol-water partition of nonzwitterionic peptides: predictive power of a molecular size-based model

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2899%2900040-1

7 January 2021

10.1016/S0168-3659(99)00040-1

Identifiers

DOI

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8 February 2018

1 reference

8 February 2018