(Q48122790)

8 February 2018

title

Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats (English)

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8 February 2018

author name string

Yu-Fang Cheng

1

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8 February 2018

Chuang Wang

2

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8 February 2018

Huan-Bing Lin

3

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8 February 2018

Yun-Feng Li

4

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8 February 2018

Ying Huang

5

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8 February 2018

Jiang-Ping Xu

6

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8 February 2018

Han-Ting Zhang

7

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8 February 2018

publication date

17 July 2010

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8 February 2018

published in

Psychopharmacology

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8 February 2018

volume

212

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8 February 2018

issue

2

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8 February 2018

page(s)

181-191

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8 February 2018

The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

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Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

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Time-dependent reorganization of brain circuitry underlying long-term memory storage

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Propentofylline improves learning and memory deficits in rats induced by beta-amyloid protein-(1-40).

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Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats

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Amyloid beta-protein(25-35) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

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12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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12 December 2020

Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells

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Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42.

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Rodent models of Alzheimer's disease: rat A beta infusion approaches to amyloid deposits

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Nasal Colivelin treatment ameliorates memory impairment related to Alzheimer's disease

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Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory.

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Rolipram and its optical isomers, phosphodiesterase 4 inhibitors, attenuated the scopolamine-induced impairments of learning and memory in rats.

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Intrahippocampal injections of exogenous beta-amyloid induce postdelay errors in an eight-arm radial maze.

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12 December 2020

Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein1-40 and ibotenic acid in rats

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12 December 2020

Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism

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12 December 2020

Impairment of hippocampal CA1 heterosynaptic transformation and spatial memory by beta-amyloid(25-35).

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12 December 2020

Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-beta1-40 in the rat.

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Toward a molecular definition of long-term memory storage

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12 December 2020

Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents

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12 December 2020

Memory deficits and increased emotionality induced by beta-amyloid (25-35) are correlated with the reduced acetylcholine release and altered phorbol dibutyrate binding in the hippocampus

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12 December 2020

Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised

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12 December 2020

Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides

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The effects of acute and repeated oroxylin A treatments on Abeta(25-35)-induced memory impairment in mice

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Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase

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Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme

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Molecular mechanisms mediating gastrin-releasing peptide receptor modulation of memory consolidation in the hippocampus.

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Long-term deprivation of oestrogens by ovariectomy potentiates beta-amyloid-induced working memory deficits in rats

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12 December 2020

Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.

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12 December 2020

A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4

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12 December 2020

Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity.

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12 December 2020

Effects of lithium and rolipram enantiomers on locomotor activity in inbred mice.

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12 December 2020

Single intracerebroventricular administration of amyloid-beta (25-35) peptide induces impairment in short-term rather than long-term memory in rats

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12 December 2020

Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action

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12 December 2020

Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus

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12 December 2020

CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila

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12 December 2020

Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons

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12 December 2020

Two different properties of short- and long-term memory

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12 December 2020

Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice

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12 December 2020

Preliminary evidence for an involvement of the cholinergic system in the sedative effects of rolipram in rats

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12 December 2020

Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear

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12 December 2020

Mycelial extract of Cordyceps ophioglossoides prevents neuronal cell death and ameliorates beta-amyloid peptide-induced memory deficits in rats

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12 December 2020

The neurochemical and behavioral effects of beta-amyloid peptide(25-35)

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12 December 2020

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

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12 December 2020

Protective effects of Glycyrrhiza uralensis Fisch. on the cognitive deficits caused by beta-amyloid peptide 25-35 in young mice

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12 December 2020

The type IV-specific phosphodiesterase inhibitor rolipram and its effect on hippocampal long-term potentiation and synaptic tagging.

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12 December 2020

Long-term memory is facilitated by cAMP response element-binding protein overexpression in the amygdala.

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12 December 2020

Dehydroevodiamine attenuates beta-amyloid peptide-induced amnesia in mice

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12 December 2020

Beta-amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield

1 reference

12 December 2020

Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory

1 reference

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus

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12 December 2020

Reversal of long-term dendritic spine alterations in Alzheimer disease models

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12 December 2020

Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid beta-infused rats.

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12 December 2020

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12 December 2020

Retrieval of memory for fear-motivated training initiates extinction requiring protein synthesis in the rat hippocampus

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12 December 2020

Behavioral effects of rolipram and structurally related compounds in mice: behavioral sedation of cAMP phosphodiesterase inhibitors

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12 December 2020

Abeta-42 deposition precedes other changes in PS-1 Alzheimer's disease

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12 December 2020

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

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12 December 2020

Catalpol ameliorates beta amyloid-induced degeneration of cholinergic neurons by elevating brain-derived neurotrophic factors.

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12 December 2020

Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction.

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12 December 2020

Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats.

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12 December 2020

Induction of amyloid precursor protein by the neurotoxic peptide, amyloid-beta 25-35, causes retinal ganglion cell death

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12 December 2020

Modulation of fibrillogenesis of amyloid beta(1-40) peptide with cationic gemini surfactant

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12 December 2020

Protective effects of compound FLZ on beta-amyloid peptide-(25-35)-induced mouse hippocampal injury and learning and memory impairment

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12 December 2020

Progressive brain dysfunction following intracerebroventricular infusion of beta(1-42)-amyloid peptide

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12 December 2020

Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease.

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12 December 2020

Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background.

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12 December 2020

Cellular mechanisms of beta-amyloid production and secretion

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12 December 2020

Interactions between the amyloid and cholinergic mechanisms in Alzheimer's disease

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12 December 2020

Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer's disease

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12 December 2020

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

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12 December 2020

Nuclear protein CBP is a coactivator for the transcription factor CREB

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12 December 2020

Nobiletin restoring beta-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats.

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12 December 2020

The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task

1 reference

12 December 2020

10.1007/S00213-010-1943-3

Identifiers

DOI

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8 February 2018

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8 February 2018