(Q48124895)
English
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT
scientific article published on 26 October 2017
Statements
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model (English)
F George Njoroge
Harold B Brooks
Stefan Thibodeaux
Alicia Torrado
Chong Si
James L Toth
Jefferson R Mc Cowan
Kenneth D Roth
Kenneth J Thrasher
Kwame Frimpong
Matthew R Lee
Robert D Dally
Timothy A Shepherd
Timothy B Durham
Brandon J Margolis
Zhipei Wu
Yong Wang
Shane Atwell
Jing Wang
Yu-Hua Hui
Timothy I Meier
Susan A Konicek
Sandaruwan Geeganage