(Q48142442)

9 February 2018

title

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion. (English)

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9 February 2018

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4

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9 February 2018

Ashley I. Bush

10

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9 February 2018

author name string

R A Cherny

1

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9 February 2018

J T Legg

2

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9 February 2018

C A McLean

3

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9 February 2018

X Huang

5

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9 February 2018

C S Atwood

6

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9 February 2018

K Beyreuther

7

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9 February 2018

R E Tanzi

8

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C L Masters

9

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language of work or name

English

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publication date

1 August 1999

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9 February 2018

Journal of Biological Chemistry

published in

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9 February 2018

volume

274

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9 February 2018

page(s)

23223-23228

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9 February 2018

issue

33

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9 February 2018

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Modified amyloid beta protein ending at 42 or 40 with different solubility accumulates in the brain of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Intramuscular desferrioxamine in patients with Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Degradation of amyloid beta-protein by a serine protease-alpha2-macroglobulin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.33.23223

21 January 2018

Identifiers

DOI

10.1074/JBC.274.33.23223

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9 February 2018

PubMed ID

10438495

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9 February 2018