(Q48144021)

9 February 2018

title

p53 compound heterozygosity in a severely affected child with Li-Fraumeni syndrome (English)

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9 February 2018

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Quesnel S

1

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9 February 2018

Verselis S

2

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9 February 2018

Portwine C

3

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9 February 2018

Garber J

4

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9 February 2018

White M

5

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9 February 2018

Feunteun J

6

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9 February 2018

Malkin D

7

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9 February 2018

Li FP

8

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9 February 2018

language of work or name

English

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publication date

1 July 1999

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9 February 2018

published in

Oncogene

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9 February 2018

volume

18

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9 February 2018

issue

27

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9 February 2018

page(s)

3970-3978

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202783

exact match

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cites work

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

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Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia

21 January 2018

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7 January 2021

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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7 January 2021

p53CP, a putative p53 competing protein that specifically binds to the consensus p53 DNA binding sites: a third member of the p53 family?

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7 January 2021

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

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A p53-dependent mouse spindle checkpoint

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WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

p53 functions as a cell cycle control protein in osteosarcomas

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7 January 2021

Gain of function mutations in p53.

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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7 January 2021

Wild-type p53 activates transcription in vitro

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7 January 2021

A simple p53 functional assay for screening cell lines, blood, and tumors

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7 January 2021

Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein

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7 January 2021

Abnormal centrosome amplification in the absence of p53.

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7 January 2021

Melanoma and soft tissue sarcoma in seven patients.

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

Are germ cell tumors part of the Li-Fraumeni cancer family syndrome?

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7 January 2021

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

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7 January 2021

p53 mutations in human cancers

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7 January 2021

P53 gene mutations in acute myelogenous leukaemia

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7 January 2021

Oligomerization is not essential for growth suppression by p53 in p53-deficient osteosarcoma Saos-2 cells

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7 January 2021

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

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7 January 2021

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Oncogenic forms of p53 inhibit p53-regulated gene expression

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7 January 2021

DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53

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7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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7 January 2021

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

Mechanisms of p53 loss in human sarcomas

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7 January 2021

Constitutional p53 mutation in a non-Li-Fraumeni cancer family

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7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

1 reference

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7 January 2021

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

p53: a frequent target for genetic abnormalities in lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

1 reference

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202783

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202783

1 reference

9 February 2018

1 reference

9 February 2018