(Q48150339)

9 February 2018

title

Pharmacokinetics and metabolism of the mixed-function hypoxic cell sensitizer prototype RSU 1069 in mice (English)

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9 February 2018

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M I Walton

1

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9 February 2018

P Workman

series ordinal

2

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9 February 2018

publication date

1 January 1988

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9 February 2018

Cancer Chemotherapy and Pharmacology

published in

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9 February 2018

volume

22

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9 February 2018

issue

4

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9 February 2018

page(s)

275-281

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9 February 2018

https://scigraph.springernature.com/pub.10.1007/bf00254231

exact match

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cites work

Structure-pharmacokinetic relationships for misonidazole analogues in mice

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12 December 2020

Studies of the in vivo and in vitro cytotoxicity of the drug RSU-1069.

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12 December 2020

Interaction of the aziridine moiety of RSU-1069 with nucleotides and inorganic phosphate. Implications for alkylation of DNA.

1 reference

12 December 2020

Induction of DNA strand breaks by RSU-1069, a nitroimidazole-aziridine radiosensitizer. Role of binding of both unreduced and radiation-reduced forms to DNA, in vitro.

1 reference

12 December 2020

Radiosensitizing and Cytotoxicity Studies with CB 1954 (2,4-Dinitro-5-Aziridinylbenzamide)

1 reference

12 December 2020

The effect of time between X-irradiation and chemotherapy on the growth of three solid mouse tumors—I. Adriamycin

1 reference

12 December 2020

Radiation sensitization and chemopotentiation: RSU 1069, a compound more efficient than misonidazole in vitro and in vivo

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12 December 2020

DNA damage in normal and neoplastic mouse tissues after treatment with misonidazole in vivo

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12 December 2020

Studies on the mechanisms of the radiosensitizing and cytotoxic properties of RSU-1069 and its analogues

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12 December 2020

Analogues of RSU-1069: radiosensitization and toxicity in vitro and in vivo

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12 December 2020

CB 1954 revisited. I. Disposition kinetics and metabolism

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12 December 2020

Significance of error associated with use of the one-compartment formula to calculate clearance of thirty-eight drugs

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12 December 2020

RSU 1069, a nitroimidazole containing an aziridine group. Bioreduction greatly increases cytotoxicity under hypoxic conditions

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12 December 2020

A toxicity and pharmacokinetic study in man of the hypoxic-cell radiosensitiser RSU-1069

1 reference

12 December 2020

Pharmacokinetic and tumour-penetration properties of the hypoxic cell radiosensitizer desmethylmisonidazole (Ro 05-Ro-9963) in dogs

1 reference

12 December 2020

Experimental pharmacokinetics of RSU-1069 and its analogues: high tumor/plasma ratios

1 reference

12 December 2020

Dose-dependence and related studies on the pharmacokinetics of misonidazole and desmethylmisonidazole in mice

1 reference

12 December 2020

Studies on the toxicity of RSU-1069

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12 December 2020

RSU 1069, a 2-nitroimidazole containing an alkylating group: high efficiency as a radio- and chemosensitizer in vitro and in vivo

1 reference

12 December 2020

Pharmacology of the mixed-function radio- and chemosensitizers CB 1954 and RSU 1069.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00254231

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9 February 2018

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9 February 2018