(Q48156868)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

title

Structure of the cold- and menthol-sensing ion channel TRPM8 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Ying Yin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Mengyu Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Lejla Zubcevic

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

William F Borschel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Seok-Yong Lee

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

author name string

Ying Yin

1

1 reference

15 July 2018

Mengyu Wu

2

1 reference

15 July 2018

Lejla Zubcevic

3

1 reference

15 July 2018

William F Borschel

4

1 reference

15 July 2018

Seok-Yong Lee

6

1 reference

15 July 2018

language of work or name

English

0 references

publication date

7 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

volume

359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

issue

6372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

page(s)

237-241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.

6 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Cryo-electron microscopy structure of the TRPV2 ion channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

RELION: implementation of a Bayesian approach to cryo-EM structure determination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

TRPM channels: same ballpark, different players, and different rules in immunogenetics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

PHENIX: a comprehensive Python-based system for macromolecular structure solution

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Inorganic polyphosphate modulates TRPM8 channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Appion: an integrated, database-driven pipeline to facilitate EM image processing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

X-ray Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded Coiled-coil

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

The menthol receptor TRPM8 is the principal detector of environmental cold

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Attenuated cold sensitivity in TRPM8 null mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

The selectivity filter of the cation channel TRPM4.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Coot: model-building tools for molecular graphics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Topology representing network enables highly accurate classification of protein images taken by cryo electron-microscope without masking.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Cryo-electron microscopy of vitrified specimens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

CTFFIND4: Fast and accurate defocus estimation from electron micrographs.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Gating of thermally activated channels.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

TRPV1 structures in distinct conformations reveal activation mechanisms

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

MolProbity: all-atom structure validation for macromolecular crystallography

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

TRPM8 is required for cold sensation in mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Bsoft: image processing and molecular modeling for electron microscopy

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Coiled coils direct assembly of a cold-activated TRP channel

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Automated molecular microscopy: the new Leginon system

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

The TRPM ion channel subfamily: molecular, biophysical and functional features.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

FindEM--a fast, efficient program for automatic selection of particles from electron micrographs

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

A TRP channel that senses cold stimuli and menthol

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5810135

14 August 2018

Identifiers

DOI

10.1126/SCIENCE.AAN4325

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29217583%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

PubMed publication ID

29217583

1 reference