(Q48165154)

English

A positron emission tomography study to assess binding of lecozotan, a novel 5-hydroxytryptamine-1A silent antagonist, to brain 5-HT1A receptors in healthy young and elderly subjects, and in patients with Alzheimer's disease

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

A positron emission tomography study to assess binding of lecozotan, a novel 5-hydroxytryptamine-1A silent antagonist, to brain 5-HT1A receptors in healthy young and elderly subjects, and in patients with Alzheimer's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Alzheimer's disease

0 references

author name string

Raje S

1

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Patat AA

2

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Parks V

3

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Schechter L

4

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Plotka A

5

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Paul J

6

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Langstrom B

7

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

language of work or name

0 references

publication date

16 May 2007

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Clinical Pharmacology & Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

83

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

1

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

86-96

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Neurotransmission--the link integrating Alzheimer research?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

[3H]WAYâ 100635 for 5â HT1A receptor autoradiography in human brain: a comparison with [3H]8â OHâ DPAT and demonstration of increased binding in the frontal cortex in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Selective labeling of 5-HT1A and 5-HT1B binding sites in bovine brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. An in vivo brain microdialysis study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Blood-brain barrier in Alzheimer dementia and in non-demented elderly. An immunocytochemical study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Effect of aging on the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Higher 5-HT1A receptor binding potential during a major depressive episode predicts poor treatment response: preliminary data from a naturalistic study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Simplified reference tissue model for PET receptor studies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C]WAY-100635 for PET.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

5-Hydroxytryptamine1A receptor occupancy by novel full antagonist 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: a[11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C]WAY-100635

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

21 January 2018

Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

7 January 2021

based on heuristic

inferred from DOI database lookup

Blood-brain barrier permeability of the demented elderly as studied by cerebrospinal fluid-serum albumin ratio.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

7 January 2021

based on heuristic

inferred from DOI database lookup

Positron emission tomography study of pindolol occupancy of 5-HT(1A) receptors in humans: preliminary analyses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

7 January 2021

based on heuristic

inferred from DOI database lookup

Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100232

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CLPT.6100232

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/17507923

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q48165154&oldid=2188271101"