(Q48219838)

English

Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection.

scientific article published on 21 August 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection. (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

prion protein family

0 references

transmembrane protein

0 references

mutational analysis

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

author name string

Richard S Stewart

1

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

language of work or name

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publication date

21 August 2003

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

278

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

46

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

45960-45968

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Prion diseases of humans and animals: their causes and molecular basis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

A Mutant Prion Protein Displays an Aberrant Membrane Association When Expressed in Cultured Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

A transmembrane form of the prion protein in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic Reticulum.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Regulation of protein topology by trans-acting factors at the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Most pathogenic mutations do not alter the membrane topology of the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Prion diseases: what is the neurotoxic molecule?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Cultured cell sublines highly susceptible to prion infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Prion protein expression in different species: analysis with a panel of new mAbs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

The signal peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Signal sequences control gating of the protein translocation channel in a substrate-specific manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Molecular distinction between pathogenic and infectious properties of the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Combinatorial Control of Prion Protein Biogenesis by the Signal Sequence and Transmembrane Domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Prion protein contains a second endoplasmic reticulum targeting signal sequence located at its C terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307833200

21 January 2018

Identifiers

10.1074/JBC.M307833200

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/12933795

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