(Q48220270)

9 February 2018

title

NF-kappaB is activated and promotes cell death in focal cerebral ischemia. (English)

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9 February 2018

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Schneider A

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9 February 2018

Martin-Villalba A

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9 February 2018

Weih F

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9 February 2018

Vogel J

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9 February 2018

Wirth T

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9 February 2018

Schwaninger M

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9 February 2018

language of work or name

English

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publication date

1 May 1999

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9 February 2018

published in

Nature Medicine

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9 February 2018

volume

5

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9 February 2018

page(s)

554-559

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9 February 2018

issue

5

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/8432

exact match

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cites work

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

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Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

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Activate NF-kappa B or die?

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NF-kappa B: a crucial transcription factor for glial and neuronal cell function

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Constitutive NF-kappa B activity in neurons

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Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro

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Seizure activity results in a rapid induction of nuclear factor-kappa B in adult but not juvenile rat limbic structures.

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Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons

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Function and activation of NF-kappa B in the immune system

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7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

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Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation

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Dominant-negative action of the jimpy mutation in mice complemented with an autosomal transgene for myelin proteolipid protein

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Selective recognition of the activated form of transcription factor NF-kappa B by a monoclonal antibody

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Monofilament intraluminal middle cerebral artery occlusion in the mouse.

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Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model.

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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Excitatory amino acids as a final common pathway for neurologic disorders.

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Flupirtine increases the levels of glutathione and Bc1-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect

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Global ischemia activates nuclear factor-kappa B in forebrain neurons of rats.

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DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

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Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

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Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

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Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

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Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-kappaB in rats.

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7 January 2021

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

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Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum.

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7 January 2021

Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.

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High constitutive NF-kappaB activity mediates resistance to oxidative stress in neuronal cells.

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Janus faces of NF-kappa B: neurodestruction versus neuroprotection

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7 January 2021

Inhibition of NF-kappa B by sodium salicylate and aspirin

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Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

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7 January 2021

Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-kappaB activation.

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7 January 2021

In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction

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7 January 2021

Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

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7 January 2021

Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy.

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7 January 2021

Early delineation of ischemic tissue in rat brain cryosections by high-contrast staining.

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A semiautomated method for measuring brain infarct volume.

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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7 January 2021

Identifiers

DOI

10.1038/8432

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9 February 2018

PubMed ID

10229233

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9 February 2018