(Q4822789)

Leucine-rich repeat domain superfamily

1 reference

Toll-like receptor 7

1 reference

Toll/interleukin-1 receptor homology (TIR) domain, protein family

1 reference

Cysteine-rich flanking region, C-terminal domain, protein family

1 reference

Leucine-rich repeat, typical subtype, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

BspA type Leucine rich repeat region, protein family

1 reference

transmembrane signaling receptor activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

double-stranded RNA binding

1 reference

8 April 2019

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

single-stranded RNA binding

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

single-stranded RNA binding

pattern recognition receptor activity

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

endoplasmic reticulum

1 reference

27 March 2018

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

endolysosome membrane

1 reference

8 April 2019

1 reference

8 April 2019

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

TAS

biological process

I-kappaB phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

immune system process

1 reference

8 April 2019

positive regulation of inflammatory response

1 reference

8 April 2019

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

toll-like receptor 9 signaling pathway

IC

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

positive regulation of interleukin-8 production

TAS

1 reference

8 April 2019

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

regulation of protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

defense response to virus

3 references

27 March 2018

Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

cellular response to mechanical stimulus

1 reference

8 April 2019

Expression of the Bcl-2 protein BAD promotes prostate cancer growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

microglial cell activation

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

positive regulation of interleukin-6 production

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

MyD88-dependent toll-like receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

positive regulation of chemokine production

1 reference

8 April 2019

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NYK1&geneProductId=UniProtKB:Q9NYK1

toll-like receptor 7 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

innate immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

inflammatory response

1 reference

8 April 2019

positive regulation of NIK/NF-kappaB signaling

1 reference

8 April 2019

Cultured human melanocytes express functional toll-like receptors 2-4, 7 and 9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

toll-like receptor signaling pathway

I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

defense response to virus

4 references

8 April 2019

Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYK1

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5003

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5051

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7198

language of work or name

17 August 2016

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL549344

Gene Atlas image

PBB GE TLR7 220146 at fs.png
732 × 530; 11 KB

0 references

has part(s)

BspA type Leucine rich repeat region

1 reference

Toll/interleukin-1 receptor homology (TIR) domain

1 reference

cysteine-rich flanking region, C-terminal

1 reference

leucine-rich repeat, typical subtype

1 reference

Leucine-rich repeat

1 reference