(Q48233851)

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Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs.

scientific article published on 13 April 2015

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25865869%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25865869%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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Pernille Tveden-Nyborg

2

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5 March 2020

Jens Lykkesfeldt

3

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5 March 2020

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Stine Hasselholt

1

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5 March 2020

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13 April 2015

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5 March 2020

British Journal of Nutrition

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5 March 2020

113

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5 March 2020

10

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5 March 2020

1539-1549

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Europe PubMed Central

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5 March 2020

Immunohistochemical study of the distribution of sodium-dependent vitamin C transporters in adult rat brain

1 reference

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21 January 2018

Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

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Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization

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21 January 2018

Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used

1 reference

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21 January 2018

Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs

1 reference

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21 January 2018

Missing step in man, monkey and guinea pig required for the biosynthesis of L-ascorbic acid

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21 January 2018

Authors' perspective: What is the optimum intake of vitamin C in humans?

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21 January 2018

Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials

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21 January 2018

Regulation of vitamin C homeostasis during deficiency

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21 January 2018

Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters

1 reference

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21 January 2018

Human choroid plexus papilloma cells efficiently transport glucose and vitamin C.

1 reference

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21 January 2018

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid

1 reference

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21 January 2018

Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2. Activation by sodium and absolute dependence on bivalent cations

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21 January 2018

Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2

1 reference

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21 January 2018

Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant

1 reference

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21 January 2018

A family of mammalian Na+-dependent L-ascorbic acid transporters

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21 January 2018

Ascorbic acid and the brain: rationale for the use against cognitive decline

1 reference

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21 January 2018

Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice

1 reference

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21 January 2018

Immunohistochemical localization of sodium-dependent L-ascorbic acid transporter 1 protein in rat kidney

1 reference

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21 January 2018

In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain.

1 reference

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21 January 2018

Cerebrospinal fluid neopterin is brain-derived and not associated with blood-CSF barrier dysfunction in non-inflammatory affective and schizophrenic spectrum disorders.

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21 January 2018

Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells

1 reference

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21 January 2018

Ascorbate concentration in human cerebrospinal fluid (CSF) and serum. Intrathecal accumulation and CSF flow rate

1 reference

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21 January 2018

Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain.

1 reference

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21 January 2018

Validation of the isotropic fractionator: comparison with unbiased stereology and DNA extraction for quantification of glial cells

1 reference

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21 January 2018

Vitamin C distribution and retention in the mouse brain

1 reference

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21 January 2018

Does vitamin C deficiency increase lifestyle-associated vascular disease progression? Evidence based on experimental and clinical studies

1 reference

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21 January 2018

Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

1 reference

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21 January 2018

Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003–2004 National Health and Nutrition Examination Survey (NHANES)

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency

1 reference

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21 January 2018

Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population.

1 reference

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21 January 2018

Behavioral and monoamine changes following severe vitamin C deficiency

1 reference

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21 January 2018

Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

Very low vitamin C activity of orally administered L-dehydroascorbic acid

1 reference

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21 January 2018

The pharmacological profile of glutamate-evoked ascorbic acid efflux measured by in vivo electrochemistry

1 reference

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21 January 2018

The glutamate aspartate transporter (GLAST) mediates L-glutamate-stimulated ascorbate-release via swelling-activated anion channels in cultured neonatal rodent astrocytes.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

Regulation of embryonic neurotransmitter and tyrosine hydroxylase protein levels by ascorbic acid

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21 January 2018

Ascorbic acid efficiently enhances neuronal synthesis of norepinephrine from dopamine

1 reference

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21 January 2018

A rat mutant unable to synthesize vitamin C.

1 reference

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21 January 2018

Aortic wall damage in mice unable to synthesize ascorbic acid

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21 January 2018

Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate

1 reference

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21 January 2018

Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function

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21 January 2018

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents

1 reference

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21 January 2018

Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants

1 reference

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21 January 2018

Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion

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21 January 2018

Promoter analysis of the human ascorbic acid transporters SVCT1 and 2: mechanisms of adaptive regulation in liver epithelial cells

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21 January 2018

Defective brain development in mice lacking the Hif-1alpha gene in neural cells

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21 January 2018

Secretion of non-helical collagenous polypeptides of alpha1(IV) and alpha2(IV) chains upon depletion of ascorbate by cultured human cells

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21 January 2018

Collagen-related abnormalities, reduction in bone quality, and effects of menatetrenone in rats with a congenital ascorbic acid deficiency

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21 January 2018

SVCT1 and SVCT2: key proteins for vitamin C uptake

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

A new recommended dietary allowance of vitamin C for healthy young women

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21 January 2018

Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2.

1 reference

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21 January 2018

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

21 January 2018

The retention of ascorbic acid by guinea-pig tissues

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21 January 2018

High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs

1 reference

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7 January 2021

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Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

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Developmental expression of GLUT1 and GLUT3 glucose transporters in rat brain.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2).

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of Ascorbic Acid and Dehydroascorbic Acid in Plasma by High-Performance Liquid Chromatography with Coulometric Detection - Are They Reliable Biomarkers of Oxidative Stress?

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Concentrations of the water-soluble vitamins thiamin, ascorbic acid, and folic acid in serum and cerebrospinal fluid of healthy individuals

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Missing step in guinea pigs required for the biosynthesis of L-ascorbic acid

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Regional distribution of ascorbate in human brain

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential compartmentalization of brain ascorbate and glutathione between neurons and glia

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

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Interactions between vitamin C and vitamin E are observed in tissues of inherently scorbutic rats

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

The vitamin C transporter SVCT2 is expressed by astrocytes in culture but not in situ

1 reference

https://api.crossref.org/works/10.1017%2FS0007114515000690

7 January 2021

based on heuristic

inferred from DOI database lookup

Relevance of endogenous ascorbate and tocopherol for brain cell vitality indicated by photon emission.

1 reference

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7 January 2021

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inferred from DOI database lookup

Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response

1 reference

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7 January 2021

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Intracellular retention of procollagen within the endoplasmic reticulum is mediated by prolyl 4-hydroxylase

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7 January 2021

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Reduction of dehydroerythorbic acid in vitamin C-deficient guinea pigs.

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7 January 2021

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Relationship between dietary intake and tissue levels of reduced and total vitamin C in the nonscorbutic guinea pig.

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7 January 2021

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Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride

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7 January 2021

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Identifiers

10.1017/S0007114515000690

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25865869%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25865869%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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