(Q48237260)

English

Post-translational import of the prion protein into the endoplasmic reticulum interferes with cell viability: a critical role for the putative transmembrane domain.

scientific article published on 8 July 2003

Post-translational Import of the Prion Protein into the Endoplasmic Reticulum Interferes with Cell Viability

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scholarly article

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

Post-translational import of the prion protein into the endoplasmic reticulum interferes with cell viability: a critical role for the putative transmembrane domain. (English)

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

prion protein family

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transmembrane protein

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endoplasmic reticulum

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Konstanze Winklhofer

2

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

5

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

author name string

Ulrich Heller

1

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

Johanna Heske

3

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

Anja Reintjes

4

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

language of work or name

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publication date

8 July 2003

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

Journal of Biological Chemistry

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Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

278

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

38

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

36139-36147

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

Prion Protein Biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Prions: health scare and biological challenge.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Prion diseases of humans and animals: their causes and molecular basis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Asparagine-linked glycosylation of the scrapie and cellular prion proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Scrapie prion protein contains a phosphatidylinositol glycolipid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

The role of disulfide bridge in the folding and stability of the recombinant human prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Membrane topology influences N-glycosylation of the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Cell-free formation of protease-resistant prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

A transmembrane form of the prion protein in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

PrP fragment 106-126 is toxic to cerebral endothelial cells expressing PrP(C).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Neurotoxicity of a prion protein fragment.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Signal sequences specify the targeting route to the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

The action of molecular chaperones in the early secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

The signal recognition particle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Protein translocation: how Hsp70 pulls it off.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Mechanism of protein translocation across the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

A novel protein complex promoting formation of functional alpha- and gamma-tubulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Geldanamycin restores a defective heat shock response in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Eps1, a novel PDI-related protein involved in ER quality control in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

De novo generation of a PrPSc-like conformation in living cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Unusual topogenic sequence directs prion protein biogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

The yeast KRE5 gene encodes a probable endoplasmic reticulum protein required for (1----6)-beta-D-glucan synthesis and normal cell growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Inhibition of complex glycosylation increases the formation of PrPsc

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Channel formation by a neurotoxic prion protein fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Channel activity of deamidated isoforms of prion protein fragment 106-126 in planar lipid bilayers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic Reticulum.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Diversity of oligosaccharide structures linked to asparagines of the scrapie prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Neurotoxicity of the Putative Transmembrane Domain of the Prion Protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Prion protein contains a second endoplasmic reticulum targeting signal sequence located at its C terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304002200

21 January 2018

Identifiers

10.1074/JBC.M304002200

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/12853456

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