(Q48261352)

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Rebalance of striatal NMDA/AMPA receptor ratio underlies the reduced emergence of dyskinesia during D2-like dopamine agonist treatment in experimental Parkinson's disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23223310

Rebalance of striatal NMDA/AMPA receptor ratio underlies the reduced emergence of dyskinesia during D2-like dopamine agonist treatment in experimental Parkinson's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23223310

0 references

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Veronica Ghiglieri

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Fabrizio Gardoni

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Barbara Picconi

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Alessandro Tozzi

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Paolo Calabresi

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

author name string

Vincenza Bagetta

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Valentina Pendolino

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Giulia Del Papa

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Carmela Giampà

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

Elisa Zianni

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 December 2012

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23223310

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

32

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

49

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

17921-17931

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa motor complications in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine-dependent synaptic plasticity in striatum during in vivo development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular segregation of distinct heteromeric NMDA glutamate receptors in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term synaptic depression in the striatum: physiological and pharmacological characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic doses of L-dopa reverse hypersensitivity of corticostriatal D2-dopamine receptors and glutamatergic overactivity in experimental parkinsonism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation and regulation of the AMPA receptor by SRC family tyrosine kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single amino acid residue determines the Ca2+ permeability of AMPA-selective glutamate receptor channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Ca2+-permeable AMPA receptors: synaptic plasticity and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New targets for pharmacological intervention in the glutamatergic synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat model of Parkinson's disease with bilateral motor abnormalities, reversible with levodopa, and dyskinesias

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ten-year follow-up of Parkinson's disease patients randomized to initial therapy with ropinirole or levodopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal regulation of dopamine D1 and D3 receptor function and trafficking by heterodimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of l-3,4-dihydroxyphenylalanine (=DOPA) on akinesia in parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms underlying levodopa-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA antagonist memantine improves levodopa-induced dyskinesias and "on-off" phenomena in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Onset of dyskinesia with adjunct ropinirole prolonged-release or additional levodopa in early Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maladaptive striatal plasticity in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphodiesterases rescues striatal long-term depression and reduces levodopa-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Milestones in Parkinson's disease therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapies for dopaminergic-induced dyskinesias in Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting NR2A-containing NMDA receptors reduces L-DOPA-induced dyskinesias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine-dependent long-term depression is expressed in striatal spiny neurons of both direct and indirect pathways: implications for Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous drug delivery in early- and late-stage Parkinson's disease as a strategy for avoiding dyskinesia induction and expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of l-DOPA-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulsatile or continuous dopaminomimetic strategies in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New pharmacological avenues for the treatment of L-DOPA-induced dyskinesias in Parkinson's disease: targeting glutamate and adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development and validation of a quality of life measure for the carers of people with Parkinson's disease (the PDQ-Carer).

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate (NMDA) receptor composition modulates dendritic spine morphology in striatal medium spiny neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiology of dopamine-denervated striatal neurons. Implications for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early treatment of Parkinson's disease with cabergoline delays the onset of motor complications. Results of a double-blind levodopa controlled trial. The PKDS009 Study Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate receptors in the mammalian central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2664-12.2012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621675&resulttype=core&format=json

15 May 2020

ResearchGate publication ID

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