(Q48267044)

English

Endosomal accumulation of Toll-like receptor 4 causes constitutive secretion of cytokines and activation of signal transducers and activators of transcription in Niemann-Pick disease type C (NPC) fibroblasts: a potential basis for glial cell activat

scientific article published in February 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Endosomal accumulation of Toll-like receptor 4 causes constitutive secretion of cytokines and activation of signal transducers and activators of transcription in Niemann-Pick disease type C (NPC) fibroblasts: a potential basis for glial cell activation in the NPC brain (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

toll-like receptor

0 references

Niemann-Pick disease

1 reference

based on heuristic

inferred from title

Niemann-Pick disease, type C1

1 reference

based on heuristic

inferred from title

author name string

Michitaka Suzuki

1

1 reference

Europe PubMed Central

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26 December 2019

Yuko Sugimoto

2

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26 December 2019

Yuki Ohsaki

3

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26 December 2019

Makoto Ueno

4

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26 December 2019

Shinsuke Kato

5

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26 December 2019

Yukisato Kitamura

6

1 reference

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26 December 2019

Hiroshi Hosokawa

7

1 reference

Europe PubMed Central

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26 December 2019

Joanna P Davies

8

1 reference

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26 December 2019

Yiannis A Ioannou

9

1 reference

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26 December 2019

Marie T Vanier

10

1 reference

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26 December 2019

Kousaku Ohno

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Haruaki Ninomiya

12

1 reference

Europe PubMed Central

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26 December 2019

language of work or name

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publication date

1 February 2007

1 reference

Europe PubMed Central

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26 December 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

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26 December 2019

27

1 reference

Europe PubMed Central

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26 December 2019

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1879-1891

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Cytokines and JAK-STAT signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of HE1 as the second gene of Niemann-Pick C disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotype-phenotype relationship of Niemann-Pick disease type C: a possible correlation between clinical onset and levels of NPC1 protein in isolated skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick disease type C: spectrum of HE1 mutations and genotype/phenotype correlations in the NPC2 group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemann-Pick C1-deficient cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration in the Niemann-Pick C mouse: glial involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on neuronal death in the mouse model of Niemann-Pick C disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick type C disease: accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein E epsilon 4 homozygosity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAK/STAT pathway in rheumatoid arthritis: Pathogenic or protective?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors induce a phagocytic gene program through p38.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of phagosome maturation by signals from toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consequences of NPC1 and NPC2 loss of function in mammalian neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis accompanied by up-regulation of TNF-alpha death pathway genes in the brain of Niemann-Pick type C disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of lipid rafts in LPS-induced signaling in a macrophage cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Jak3, STAT1, STAT4, and STAT6 in inflammatory arthritis: unique Jak3 and STAT4 expression in dendritic cells in seropositive rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors in central nervous system glial inflammation and homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of interleukin-6 by minocycline in a rat model of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary tangles in Niemann-Pick disease type C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebellar degeneration in the Niemann-Pick type C mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STATs: signal transducers and activators of transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17314284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5282-06.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

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