(Q48290626)

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Ventral tegmental transcriptome response to intermittent nicotine treatment and withdrawal in BALB/cJ, C57BL/6ByJ, and quasi-congenic RQI mice

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Ventral tegmental transcriptome response to intermittent nicotine treatment and withdrawal in BALB/cJ, C57BL/6ByJ, and quasi-congenic RQI mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

0 references

4

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

author name string

Csaba Vadasz

1

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Mariko Saito

2

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Danielle O'Brien

3

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Grant Morahan

5

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Goutam Chakraborty

6

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Ray Wang

7

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

publication date

1 March 2007

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

Neurochemical Research

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

32

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

3

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

457-480

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

https://scigraph.springernature.com/pub.10.1007/s11064-006-9250-4

0 references

The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity

1 reference

https://api.crossref.org/works/10.1007%2FS11064-006-9250-4

21 January 2018

Correlation between protein and mRNA abundance in yeast

1 reference

https://api.crossref.org/works/10.1007%2FS11064-006-9250-4

21 January 2018

Functions of the orexinergic/hypocretinergic system

1 reference

https://api.crossref.org/works/10.1007%2FS11064-006-9250-4

21 January 2018

Calcitonin gene-related peptide rapidly downregulates nicotinic receptor function and slowly raises intracellular Ca2+ in rat chromaffin cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microarray technology and its application on nicotine research

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nature and identification of quantitative trait loci: a community's view

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying biological themes within lists of genes with EASE

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

7-Ketocholesterol-induced apoptosis. Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin gene-related peptide in the brain, spinal cord, and some peripheral systems.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor gene expression profiling after acute intermittent nicotine treatment in the rat cerebral cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced nNOS expression induced by repeated nicotine treatment in mu-opioid receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Region-specific transcriptional response to chronic nicotine in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining mapping and arraying: An approach to candidate gene identification.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase C gamma in distinct regions of the ventral tegmental area differentially regulates morphine-induced locomotor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microarray analysis of nicotine-induced changes in gene expression in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidimensional local false discovery rate for microarray studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dopamine D3 receptor expression accompanying behavioral sensitization to nicotine in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of gene expression surveyed in maize, mouse and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothalamic orexin-A binding sites are downregulated by chronic nicotine treatment in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ets ternary complex transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of morphine analgesia in alphaCGRP mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strain and sex differences in repeated ethanol treatment-induced motor activity in quasi-congenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The landscape of genetic complexity across 5,700 gene expression traits in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic dissection of transcriptional regulation in budding yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: a potential basis for the pro-inflammatory effects of nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine administration enhances NPY expression in the rat hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Empirical Bayes screening of many p-values with applications to microarray studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine coregulates multiple pathways involved in protein modification/degradation in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic characterization of two introgression strains (B6.Cb4i5) for the analysis of QTLs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetical genomics: the added value from segregation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CGRP-like immunoreactivity in A11 dopamine neurons projecting to the spinal cord and a note on CGRP-CCK cross-reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for lateral hypothalamic orexin neurons in reward seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caffeine and amphetamine produce cross-sensitization to nicotine-induced locomotor activity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-dependent changes in transcriptional profiles within five rat brain regions in response to nicotine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitization of the mesoaccumbens dopamine response to nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the mesotelencephalic dopamine system by quantitative-trait locus introgression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurobiology of tobacco dependence: a preclinical perspective on the role of the dopamine projections to the nucleus accumbens [corrected].

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine-induced sensitization in mice: changes in locomotor activity and mesencephalic gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine up-regulates expression of orexin and its receptors in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of neuronal gene expression with laser capture microdissection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scanning of five chromosomes for alcohol consumption loci

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional relevance of G-protein-coupled-receptor-associated proteins, exemplified by receptor-activity-modifying proteins (RAMPs).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of nicotinic ACh receptors: shaping cholinergic signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drugs of abuse and immediate-early genes in the forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the rat vesicular acetylcholine transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered profile of gene expression in rat hearts induced by chronic nicotine consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of nicotine-induced behavioral sensitization in micro-opioid receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholecystokinin (CCK) and the CCKA receptor gene polymorphism, and smoking behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine effects on the activity of mice exposed prenatally to the nicotinic agonist anatoxin-a

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical Methods for Identifying Differentially Expressed Genes in DNA Microarrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A note on using permutation-based false discovery rate estimates to compare different analysis methods for microarray data

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of nicotinic receptor expression by the ubiquitin-proteasome system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using in vitro models for expression profiling studies on ethanol and drugs of abuse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of a customized pathway-focused microarray for gene expression profiling of cellular homeostasis upon exposure to nicotine in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of neuronal nicotinic receptor function by the neuropeptides CGRP and substance P on autonomic nerve cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the role of nitric oxide in nicotine-induced locomotor sensitization in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic composition of the recombinant congenic strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine modulates the expression of a diverse set of genes in the neuronal SH-SY5Y cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine and acetylcholine induce release of calcitonin gene-related peptide from rat trachea

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring the regulation of the expression of ChAT and VAChT genes in NG108-15 cells: implication of PKA and PI3K signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin gene-related peptide regulates muscle acetylcholine receptor synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium channel antagonists suppress nicotine-induced place preference and locomotor sensitization in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying differentially expressed genes using false discovery rate controlling procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tools and strategies for physiological genomics: the Rat Genome Database

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction of null statistics in permutation-based multiple testing for multi-factorial microarray experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin gene-related peptide enhances the rate of desensitization of the nicotinic acetylcholine receptor in cultured mouse muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for coexistence of dopamine and CCK in meso-limbic neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of brain dopamine system-specific quantitative trait loci onto a C57BL/6ByJ background.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular protein PRA1 modulates the anti-apoptotic activity of Epstein-Barr virus BHRF1, a homologue of Bcl-2, through direct interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17268848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-006-9250-4

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/17268848

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