(Q48297819)

10 February 2018

title

The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells (English)

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10 February 2018

author name string

Yutaro Obara

series ordinal

1

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10 February 2018

Angela M Horgan

series ordinal

2

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10 February 2018

Philip J S Stork

series ordinal

3

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10 February 2018

language of work or name

English

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publication date

24 January 2007

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10 February 2018

Journal of Neurochemistry

published in

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10 February 2018

volume

101

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10 February 2018

issue

2

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10 February 2018

page(s)

470-482

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10 February 2018

Free cyclic AMP increases in PC12 cells on depolarization

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Pituitary adenylyl cyclase-activating peptide stimulates extracellular signal-regulated kinase 1 or 2 (ERK1/2) activity in a Ras-independent, mitogen-activated protein Kinase/ERK kinase 1 or 2-dependent manner in PC12 cells

21 January 2018

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Extracellular potassium concentration regulates proliferation of immature cerebellar granule cells

21 January 2018

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Contribution of Ca2+ calmodulin-dependent protein kinase II and mitogen-activated protein kinase kinase to neural activity-induced neurite outgrowth and survival of cerebellar granule cells

21 January 2018

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Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells

21 January 2018

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Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

21 January 2018

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CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

21 January 2018

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Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

21 January 2018

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Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4.

21 January 2018

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RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

21 January 2018

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Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus.

21 January 2018

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A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

21 January 2018

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Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

21 January 2018

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Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

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Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor.

21 January 2018

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Pituitary adenylate cyclase-activating polypeptide promotes cell survival and neurite outgrowth in rat cerebellar neuroblasts

21 January 2018

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Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis

21 January 2018

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Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity

21 January 2018

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Up-regulation of the PACAP type-1 receptor (PAC1) promoter by neurotrophins in rat PC12 cells and mouse cerebellar granule cells via the Ras/mitogen-activated protein kinase cascade

21 January 2018

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A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

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Analysis of the role of the mitogen-activated protein kinase in mediating cyclic-adenosine 3',5'-monophosphate effects on prolactin promoter activity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptides stimulate mitogen-activated protein kinase in the pituitary cell line GH4C1 by a 3',5'-cyclic adenosine monophosphate pathway

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Neuronal activity-dependent cell survival mediated by transcription factor MEF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Cellular Factors Binding to a Novel cis-Acting Element Mediate Steroid Hormone Responsiveness of Mouse Mammary Tumor Virus Promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

SPAL, a Rap-specific GTPase activating protein, is present in the NMDA receptor-PSD-95 complex in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Calcium activation of ERK mediated by calmodulin kinase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Calmodulin-dependent kinase kinase/calmodulin kinase I activity gates extracellular-regulated kinase-dependent long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Differential signal transduction by five splice variants of the PACAP receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Activation of the mitogen-activated protein kinase (ERK(1/2)) signaling pathway by cyclic AMP potentiates the neuroprotective effect of the neurotransmitter noradrenaline on dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Cyclic AMP activates Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Pituitary adenylate cyclase-activating polypeptide stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Signaling pathways for PC12 cell differentiation: making the right connections

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Coupling of cAMP/PKA and MAPK signaling in neuronal cells is dependent on developmental stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Calmodulin-regulated adenylyl cyclases and neuromodulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Involvement of mitogen-activated protein kinase in cyclic adenosine 3',5'-monophosphate-induced hormone gene expression in rat pituitary GH(3) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

Ras and Rap control AMPA receptor trafficking during synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04390.X

10.1111/J.1471-4159.2006.04390.X

21 January 2018

Identifiers

DOI

1 reference

10 February 2018

1 reference

10 February 2018