(Q48298661)

English

Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease.

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scholarly article

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/17251422

Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease. (English)

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/17251422

Alzheimer's disease

0 references

Marcelo O Dietrich

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

Ignacio Torres Aleman

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

author name string

Cristina Lopez-Lopez

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

Friedrich Metzger

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

Hansruedi Loetscher

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

language of work or name

0 references

publication date

1 January 2007

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/17251422

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

27

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

824-831

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid peptides are cytotoxic to astrocytes in culture: a role for oxidative stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-I stimulates dephosphorylation of ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired cerebromicrovascular perfusion. Summary of evidence in support of its causality in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of insulin-like growth factor-1 on retinal endothelial cell glucose transport and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cerebromicrovasculature: a key player in the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum insulin-like growth factor I regulates brain amyloid-beta levels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the growth hormone-insulin-like growth factor axis in glucose homeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential roles of insulin and IGF-1 in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A microplate assay for the detection of oxidative products using 2',7'-dichlorofluorescin-diacetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AMP-activated protein kinase cascade--a unifying system for energy control

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt2, a novel functional link between p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways in myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurovascular regulation in the normal brain and in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I is required for vessel remodeling in the adult brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor: basic science and clinical progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depression of cell metabolism and proliferation by membrane-permeable and -impermeable modulators: role for AMP-to-ATP ratio.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mitochondrial respiration by nitric oxide: its role in glucose metabolism and neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From angiogenesis to neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered regulation of brain glucose metabolism as a cause of neurodegenerative disorders?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface-weighted star volume: concept and estimation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17251422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4345-06.2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672921&resulttype=core&format=json

16 May 2020

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