(Q48300034)

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By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke

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17 February 2020

By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke (English)

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17 February 2020

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ChEBI release 2020-05-28

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Shaojing Li

1

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17 February 2020

Chuanhong Wu

2

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17 February 2020

Li Zhu

3

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17 February 2020

Jian Gao

4

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17 February 2020

Jing Fang

5

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17 February 2020

Defeng Li

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17 February 2020

Meihong Fu

7

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17 February 2020

Rixin Liang

8

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17 February 2020

Lan Wang

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17 February 2020

Ming Cheng

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17 February 2020

Hongjun Yang

11

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17 February 2020

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9 November 2012

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17 February 2020

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17 February 2020

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17 February 2020

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17 February 2020

13403-13423

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17 February 2020

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9 November 2012

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The flavonoid scaffold as a template for the design of modulators of the vascular Ca(v) 1.2 channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effect of Bacopa monniera on ischemia induced brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astaxanthin reduces ischemic brain injury in adult rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gingko biloba extract (EGb 761) attenuates the focal cerebral ischemic injury-induced decrease in astrocytic phosphoprotein PEA-15 levels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-ischemic activation of protein kinase C ε protects the hippocampus from cerebral ischemic injury via alterations in cerebral blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible middle cerebral artery occlusion without craniectomy in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

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Cornin ameliorates cerebral infarction in rats by antioxidant action and stabilization of mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

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Review of laser speckle contrast techniques for visualizing tissue perfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vasorelaxant effect of the flavonoid galangin on isolated rat thoracic aorta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

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The cost of cerebral ischaemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment with eplerenone reduces stroke volume in mouse middle cerebral artery occlusion model

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study on permeability transition pore opening and cytochrome c release from mitochondria, induced by caspase-3 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the induction of apoptosis by endosulfan in a human T-cell leukemic line

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection of ginsenoside Re in cerebral ischemia-reperfusion injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic pre-conditioning preserves brain mitochondrial functions during the middle cerebral artery occlusion in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical stroke research--advantages and disadvantages of the most common rodent models of focal ischaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral hemodynamics and investigations of cerebral blood flow regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laser speckle contrast imaging in biomedical optics

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial targets for stroke: focusing basic science research toward development of clinically translatable therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

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boc-Aspartyl(OMe)-fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of galangin supplementation on oxidative damage and inflammatory changes in fructose-fed rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay of mitochondrial functions by resazurin in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic preconditioning targets the respiration of synaptic mitochondria via protein kinase C epsilon

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ channel antagonists and neuroprotection from cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-oxidant and anti-apoptotic effects of nebivolol and zofenopril in a model of cerebral ischemia/reperfusion in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

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Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

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The potential role of honey and its polyphenols in preventing heart diseases: a review

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Anticholinergics may play more roles in chronic obstructive pulmonary disease

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https://pubmed.ncbi.nlm.nih.gov/23143152

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Alterations of rCBF and mitochondrial dysfunction in major depressive disorder: a case report

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Baicalein protects rat brain mitochondria against chronic cerebral hypoperfusion-induced oxidative damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

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Alterations in mitochondrial function and spermatozoal motility in goat spermatozoa following incubation with a human lysozyme plasmid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

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Ginkgo biloba extract EGb761 protects against aging-associated mitochondrial dysfunction in platelets and hippocampi of SAMP8 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laser Doppler, speckle and related techniques for blood perfusion mapping and imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

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based on heuristic

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Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ginkgo biloba extract (EGb761) inhibits mitochondria-dependent caspase pathway and prevents apoptosis in hypoxia-reoxygenated cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23143152

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES171113403

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143152%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143152%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143152%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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