(Q48319815)

English

Cholesterol and oxygenated cholesterol concentrations are markedly elevated in peripheral tissue but not in brain from mice with the Niemann-Pick type C phenotype.

scientific article published in December 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

Cholesterol and oxygenated cholesterol concentrations are markedly elevated in peripheral tissue but not in brain from mice with the Niemann-Pick type C phenotype. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

author name string

G S Tint

1

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

P Pentchev

2

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

G Xu

3

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

A K Batta

4

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

S Shefer

5

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

G Salen

6

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

A Honda

7

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

publication date

1 December 1998

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

Journal of Inherited Metabolic Disease

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

21

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

8

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

853-863

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

https://scigraph.springernature.com/pub.10.1023/a:1005474803278

0 references

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick disease type C: diagnosis and outcome in children, with particular reference to liver disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological activities of oxysterols

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidized low density lipoprotein in atherogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type C Niemann-Pick disease: documentation of abnormal LDL processing in lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal Niemann-Pick disease type C: ultrastructural and lipid findings in liver and spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipids of human atheroma Part 4. Characterisation of a new group of polar sterol esters from human atherosclerotic plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of Niemann-Pick disease type D to the same region of human chromosome 18 as Niemann-Pick disease type C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A case of juvenile lipidosis: electron microscopic, histochemical and biochemical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juvenile dystonic lipidosis (variant of Niemann-Pick disease type C).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of mevalonate and 7 alpha-hydroxycholesterol in human plasma by gas chromatography-mass spectrometry as indices of cholesterol and bile acid biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Sterol Synthesis in Cultured Mouse Cells by 7α-Hydroxycholesterol, 7β-Hydroxycholesterol, and 7-Ketocholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fecal bile acids and sterols of Alligator mississippiensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the role of sterol hydroperoxides in steroid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoprotein oxidation and lipoprotein-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Esterified and total 7 alpha-hydroxycholesterol in human serum as an indicator for hepatic bile acid synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosome lipid storage disorder in NCTR-BALB/c mice. I. Description of the disease and genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the possible use of the serum level of 7 alpha-hydroxycholesterol as a marker for increased activity of the cholesterol 7 alpha-hydroxylase in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic storage disorder in BALB/C mice with a metabolic block in esterification of exogenous cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick disease. Morphologic and biochemical studies in the visceral form with late central nervous system involvement (Crocker's group C).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosome lipid storage disorder in NCTR-BALB/c mice. III. Isolation and analysis of storage inclusions from liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A lysosomal storage disorder in mice: a model of Niemann-Pick disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of HDL2-dependent synthesis of bile acids in culture of rabbit hepatocytes: effects of oxidized cholesterol derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-pick disease type D: Lipid analyses and studies on sphingomyelinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7 beta-hydroperoxycholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosome lipid storage disorder in NCTR-BALB/c mice. II. Morphologic and cytochemical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay of cholesterol 7 alpha-hydroxylase utilizing a silica cartridge column and 5 alpha-cholestane-3 beta, 7 beta-diol as an internal standard

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of 3-oxygenated delta 4 and delta 5 - C27 steroids by soybean lipoxygenase and rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical studies in Niemann-Pick disease. I. Major sphingolipids of liver and spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxysterols, cholesterol biosynthesis, and vascular endothelial cell monolayer barrier function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the early reduction of the 24,25 double bond in the conversion of lanosterol to cholesterol in cerebrotendinous xanthomatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of regulatory oxysterols, 32-oxolanosterol and 32-hydroxylanosterol in mevalonate-treated cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic abnormalities in feline Niemann-Pick type C heterozygotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotoxicity and arteriosclerosis due to contaminants of USP-grade cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of dietary 7-ketocholesterol, inhibitor of sterol synthesis, on hepatic microsomal cholesterol 7 alpha-hydroxylase activity in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cholesterol storage disorder of the mutant BALB/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of oxidatively modified LDL on cholesterol esterification in cultured macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sphingomyelinosis, a new mutation in the mouse: a model of Niemann-Pick disease in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous assay of the activities of two key enzymes in cholesterol metabolism by gas chromatography-mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/9870211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1005474803278

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/9870211

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