(Q48331516)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

author name string

M J O'Neill

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

A Bond

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

M A Ward

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

C A Hicks

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

K Hoo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

D Bleakman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

D Lodge

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

publication date

1 October 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

Neuropharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

issue

10-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

page(s)

1211-1222

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate

7 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

GYKI 52466 blocks the increase in extracellular glutamate induced by ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Brain cooling during transient focal ischemia provides complete neuroprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

AMPA receptor antagonists and local cerebral glucose utilization in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Neuroprotective effect of the AMPA receptor antagonist LY-293558 in focal cerebral ischemia in the cat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Glutamate neurotoxicity in cortical cell culture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

inferred from DOI database lookup

7 January 2021

based on heuristic

A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

MK-801 reduced cerebral ischemic injury by inducing hypothermia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Protection against ischemic hippocampal CA1 damage in the rat with a new non-NMDA antagonist, NBQX

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

The neuroprotective effects of the decahydroisoquinoline, LY 215490; a novel AMPA antagonist in focal ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

The pharmacotherapy of focal cortical ischaemia in the mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Combined postischemic hypothermia and delayed MK-801 treatment attenuates neurobehavioral deficits associated with transient global ischemia in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

CGS-19755, a competitive NMDA receptor antagonist, reduces calcium-calmodulin binding and improves outcome after global cerebral ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Brain temperature and the neuroprotective action of enadoline and dizocilpine in the gerbil model of global ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

YM90K, an AMPA antagonist, has no neurotoxic effects on cerebrocortical neurons in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Protection against post-ischemic behavioral pathology by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) in the gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

YM90K, a selective-amino-3-hydroxy5-methyl-4-isoxazole propionate (AMPA) receptor antagonist, prevents induction of heat shock protein HSP -70 and hsp -70 mRNA in rat retrosplenial cortex by phencyclidine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Neuroprotection after several days of mild, drug-induced hypothermia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

NMDA Antagonist Neurotoxicity: Mechanism and Prevention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

(3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

(3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, absolute stereochemical preferences, and in vivo activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Efficacy of D-CPPene, a competitive N-methyl-D-aspartate antagonist in focal cerebral ischemia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

AMPA receptor antagonism attenuates MK-801-induced hypermetabolism in the posterior cingulate cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

In vitro and in vivo antagonism of AMPA receptor activation by (3S, 4aR, 6R, 8aR)-6-[2-(1(2)H-tetrazole-5-yl) ethyl] decahydroisoquinoline-3-carboxylic acid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Comparison of the patterns of altered cerebral glucose utilisation produced by competitive and non-competitive NMDA receptor antagonists.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Immediate or delayed mild hypothermia prevents focal cerebral infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

Neuroprotective effect of YM90K, a novel AMPA/kainate receptor antagonist, in focal cerebral ischemia in cats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2898%2900134-8

10.1016/S0028-3908(98)00134-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9849659%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference