(Q48335317)

10 February 2018

title

Exploring the role of pH in modulating the effects of lidocaine in virtual ischemic tissue. (English)

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10 February 2018

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5

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10 February 2018

Beatriz Trenor

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ORCID Public Data File 2021

author name string

Karen Cardona

1

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10 February 2018

Beatriz Trénor

2

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10 February 2018

Germán Moltó

3

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10 February 2018

Miguel Martínez

4

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10 February 2018

Frank Starmer

6

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10 February 2018

Javier Saiz

7

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10 February 2018

publication date

13 August 2010

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10 February 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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10 February 2018

volume

299

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10 February 2018

issue

5

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10 February 2018

page(s)

H1615-24

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10 February 2018

Conduction velocity depression and drug-induced ventricular tachyarrhythmias. Effects of lidocaine in the intact canine heart

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Asymptotic properties of mathematical models of excitability.

21 January 2018

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Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium

21 January 2018

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Selective depression of maximum rate of depolarization of guinea-pig ventricular action potentials by amiodarone and lignocaine in simulated ischaemia: comparison with encainide

21 January 2018

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Protection against ventricular arrhythmias and cardiac death using adenosine and lidocaine during regional ischemia in the in vivo rat.

21 January 2018

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The effects of lidocaine on intracellular and extracellular potentials, activation, and ventricular arrhythmias during acute regional ischemia in the isolated porcine heart

21 January 2018

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Spiral waves and reentry dynamics in an in vitro model of the healed infarct border zone

21 January 2018

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Ischemic modulation of vulnerable period and the effects of pharmacological treatment of ischemia-induced arrhythmias: a simulation study.

21 January 2018

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Evidence for voltage-dependent block of cardiac sodium channels by tetrodotoxin

21 January 2018

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Mechanisms of atrial fibrillation termination by rapidly unbinding Na+ channel blockers: insights from mathematical models and experimental correlates

21 January 2018

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Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance

21 January 2018

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Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study

21 January 2018

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Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts.

21 January 2018

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Simulation of action potentials from metabolically impaired cardiac myocytes. Role of ATP-sensitive K+ current.

21 January 2018

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An analysis of lidocaine block of sodium current in isolated human atrial and ventricular myocytes.

21 January 2018

1 reference

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The influence of pH on th electrophysiological effects of lidocaine in guinea pig ventricular myocardium

21 January 2018

1 reference

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Modelling of frequency-dependent effects of lignocaine homologues on the maximum upstroke velocity of action potentials in guinea-pig papillary muscles

21 January 2018

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Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

21 January 2018

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Region [corrected] of slowed conduction acts as core for spiral wave reentry in cardiac cell monolayers

21 January 2018

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Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues

21 January 2018

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A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes

21 January 2018

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Quantitative modelling of interaction of propafenone with sodium channels in cardiac cells

21 January 2018

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Local anesthetics. Effect of pH on use-dependent block of sodium channels in frog muscle

21 January 2018

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Molecular basis of arrhythmias

21 January 2018

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Electrical Heterogeneity and Arrhythmogenesis: Importance of Conduction Velocity Dispersion

21 January 2018

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Artificial neural network modeling and genetic algorithm based medium optimization for the improved production of marine biosurfactant

21 January 2018

1 reference

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Modeling ion channel blockade at guarded binding sites: application to tertiary drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

Interaction of lidocaine with the cardiac sodium channel: effects of low extracellular pH are consistent with an external blocking site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

Combined blockade of the Na+ channel and the Na+/H+ exchanger virtually prevents ischemic Na+ overload in rat hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

pH dependence of kinetics and steady-state block of cardiac sodium channels by lidocaine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

Effects of hyperkalaemia on the depression of maximum rate of depolarization by class I antiarrhythmic agents in guinea-pig myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

Na channel activation gate modulates slow recovery from use-dependent block by local anesthetics in squid giant axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

Actions of lidocaine on reentrant ventricular rhythms in the subacute myocardial infarction period in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00425.2010

10.1152/AJPHEART.00425.2010

21 January 2018

Identifiers

DOI

1 reference

10 February 2018

PubMed ID

20709860

1 reference

10 February 2018