(Q48347429)

10 February 2018

title

Precursor RNAs harboring nonsense codons accumulate near the site of transcription. (English)

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10 February 2018

author

Noélia Custódio

5

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10 February 2018

Maria do Carmo Fonseca

6

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10 February 2018

author name string

Mühlemann O

1

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10 February 2018

Mock-Casagrande CS

2

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10 February 2018

Wang J

3

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10 February 2018

Li S

4

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10 February 2018

Wilkinson MF

7

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10 February 2018

Moore MJ

8

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10 February 2018

publication date

1 July 2001

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10 February 2018

published in

Molecular Cell

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10 February 2018

volume

8

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10 February 2018

issue

1

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10 February 2018

page(s)

33-43

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10 February 2018

Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis

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Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability

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Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

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7 January 2021

Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping

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Identification of a regulated pathway for nuclear pre-mRNA turnover.

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7 January 2021

Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.

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7 January 2021

Infrequent translation of a nonsense codon is sufficient to decrease mRNA level

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7 January 2021

A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

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7 January 2021

Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

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7 January 2021

Isolation of new nonsense and frameshift mutants in the immunoglobulin mu heavy-chain gene of hybridoma cells

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7 January 2021

The regulation of splice-site selection, and its role in human disease

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7 January 2021

Inefficient processing impairs release of RNA from the site of transcription

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7 January 2021

Maintenance of an open reading frame as an additional level of scrutiny during splice site selection

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7 January 2021

The skipping of constitutive exons in vivo induced by nonsense mutations

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7 January 2021

Nuclear eukaryotic initiation factor 4E (eIF4E) colocalizes with splicing factors in speckles

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7 January 2021

New species of human tyrosine hydroxylase mRNA are produced in variable amounts in adrenal medulla and are overexpressed in progressive supranuclear palsy

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7 January 2021

Nonsense-mediated mRNA decay in health and disease

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7 January 2021

A premature termination codon in either exon of minute virus of mice P4 promoter-generated pre-mRNA can inhibit nuclear splicing of the intervening intron in an open reading frame-dependent manner

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7 January 2021

A premature termination codon interferes with the nuclear function of an exon splicing enhancer in an open reading frame-dependent manner

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7 January 2021

A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.

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7 January 2021

A perfect message: RNA surveillance and nonsense-mediated decay

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7 January 2021

Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain

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7 January 2021

Contribution of growing RNA molecules to the nuclear transcripts foci observed by FISH

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7 January 2021

Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA.

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7 January 2021

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

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7 January 2021

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

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7 January 2021

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

1 reference

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7 January 2021

T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons: a nuclear-associated translation-like mechanism

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7 January 2021

Nonsense surveillance in lymphocytes?

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7 January 2021

Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Pem: a testosterone- and LH-regulated homeobox gene expressed in mouse Sertoli cells and epididymis.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Proofreading and aminoacylation of tRNAs before export from the nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Coupling of transcription and translation in Dictyostelium discoideum nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Nopp 140 shuttles on tracks between nucleolus and cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Highly localized tracks of human immunodeficiency virus type 1 Nef in the nucleus of cells of a human CD4+ T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells

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7 January 2021

Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Activation of RNA polymerase III transcription of human Alu repetitive elements by adenovirus type 5: requirement for the E1b 58-kilodalton protein and the products of E4 open reading frames 3 and 6.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

The nucleolus and the four ribonucleoproteins of translation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Review: movement of mRNA from transcription site to nuclear pores

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Disruption of the splicing enhancer sequence within exon 27 of the dystrophin gene by a nonsense mutation induces partial skipping of the exon and is responsible for Becker muscular dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Frameshift mutations in the v-src gene of avian sarcoma virus act in cis to specifically reduce v-src mRNA levels

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Binary specification of nonsense codons by splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

A splicing enhancer exhibits both constitutive and regulated activities

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Nonsense mutations in the dihydrofolate reductase gene affect RNA processing

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

The association of nonsense codons with exon skipping

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

The role of exon sequences in splice site selection.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Nonsense-mediated mRNA decay in Xenopus oocytes and embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900288-X

7 January 2021

10.1016/S1097-2765(01)00288-X

Identifiers

DOI

1 reference

10 February 2018

1 reference

10 February 2018