(Q48348716)

10 February 2018

title

Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice. (English)

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10 February 2018

author name string

O'Brien RL

series ordinal

1

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10 February 2018

Brinster RL

series ordinal

2

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10 February 2018

Storb U

series ordinal

3

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10 February 2018

language of work or name

English

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publication date

1 March 1987

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10 February 2018

published in

Nature

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10 February 2018

volume

326

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10 February 2018

issue

6111

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10 February 2018

page(s)

405-409

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10 February 2018

https://scigraph.springernature.com/pub.10.1038/326405a0

exact match

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cites work

Genetic Control of Antibody Variable Regions

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7 January 2021

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

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7 January 2021

Somatic mutation of immunoglobulin light-chain variable-region genes.

1 reference

7 January 2021

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody.

1 reference

7 January 2021

Antibody diversity: somatic hypermutation of rearranged VH genes

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7 January 2021

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

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7 January 2021

Clusters of point mutations are found exclusively around rearranged antibody variable genes

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7 January 2021

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

1 reference

7 January 2021

Somatic mutations of immunoglobulin variable genes are restricted to the rearranged V gene.

1 reference

7 January 2021

Somatic diversification of immunoglobulins.

1 reference

7 January 2021

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

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7 January 2021

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

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7 January 2021

Somatic mutation and clonal expansion of B cells in an antigen-driven immune response.

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7 January 2021

Polymorphism in immunoglobulin heavy chains suggesting gene conversion

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7 January 2021

Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies

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7 January 2021

Somatic diversification is required to generate the V kappa genes of MOPC 511 and MOPC 167 myeloma proteins

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7 January 2021

Diversity in the germline antibody repertoire. Molecular evolution of the T15 VN gene family

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7 January 2021

The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes

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7 January 2021

Somatic evolution of variable region structures during an immune response

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7 January 2021

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line

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7 January 2021

Somatic Mutants and Antibody Diversity

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7 January 2021

The isolation of hybrid cell lines producing monoclonal antibodies against the p15(E) protein of ecotropic murine leukemia viruses

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7 January 2021

Anti-phosphocholine hybridoma antibodies. I. Direct evidence for three distinct families of antibodies in the murine response

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7 January 2021

57 Sequencing end-labeled DNA with base-specific chemical cleavages

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7 January 2021

DNA sequencing with chain-terminating inhibitors

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7 January 2021

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

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7 January 2021

A method for the recovery of DNA from agarose gels

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7 January 2021

Detection of specific sequences among DNA fragments separated by gel electrophoresis

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7 January 2021

Identifiers

DOI

10.1038/326405A0

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10 February 2018

Dimensions Publication ID

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10 February 2018