(Q48350826)

10 February 2018

title

Modulation of acrylonitrile-induced embryotoxicity in vitro by glutathione depletion. (English)

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10 February 2018

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A M Saillenfait

1

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10 February 2018

J P Payan

2

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I Langonné

3

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D Beydon

4

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10 February 2018

M C Grandclaude

5

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J P Sabaté

6

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J de Ceaurriz

7

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10 February 2018

publication date

1 January 1993

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10 February 2018

published in

Archives of Toxicology

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10 February 2018

volume

67

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10 February 2018

issue

3

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10 February 2018

page(s)

164-172

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10 February 2018

https://scigraph.springernature.com/pub.10.1007/bf01973303

exact match

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cites work

Effect of glutathione depletion by buthionine sulfoximine on rat embryonic development in vitro

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12 December 2020

Regulation of intracellular glutathione in rat embryos and visceral yolk sacs and its effect on 2-nitrosofluorene-induced malformations in the whole embryo culture system.

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12 December 2020

In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats.

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12 December 2020

Differential glutathione depletion by L-buthionine-S,R-sulfoximine in rat embryo versus visceral yolk sac in vivo and in vitro

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12 December 2020

Cytochrome P-450-dependent biotransformation of a series of phenoxazone ethers in the rat conceptus during early organogenesis: evidence for multiple P-450 isoenzymes

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12 December 2020

Quantitation of rat embryonic development in vitro: A morphological scoring system

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12 December 2020

Enhancement of the embryotoxicity of acrolein, but not phosphoramide mustard, by glutathione depletion in rat embryos in vitro

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12 December 2020

Teratogenic effects of aliphatic nitriles

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12 December 2020

Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis

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12 December 2020

Acrylonitrile: in vivo metabolism in rats and mice

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12 December 2020

Embryotoxicity of acrylonitrile in whole-embryo culture.

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12 December 2020

Metabolism of acrylonitrile by isolated rat hepatocytes

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12 December 2020

In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids

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12 December 2020

Teratogenicity of acrylonitrile given to rats by gavage or by inhalation

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12 December 2020

Tissue sulfhydryl groups

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12 December 2020

Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: influence of dose and route of administration

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12 December 2020

Identification of the major urinary metabolites of acrylonitrile in the rat.

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12 December 2020

Effect of glutathione depletion on the uptake of acrylonitrile vapors and on its irreversible association with tissue macromolecules

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12 December 2020

Acrylonitrile and tissue glutathione: differential effect of acute and chronic interactions

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12 December 2020

Acrylonitrile depletes glutathione without changing calcium sequestration in hepatic microsomes and mitochondria

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12 December 2020

Styrene and acrylonitrile induced depression of hepatic nonprotein sulfhydryl content in various rodent species

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12 December 2020

Determination of penicillamine and other thiols by combined high-performance liquid chromatography and post-column reaction with Ellman's reagent: application to human urine

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12 December 2020

Formation of mercapturic acids from acrylonitrile, crotononitrile, and cinnamonitrile by direct conjugation and via an intermediate oxidation process

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12 December 2020

Whole-embryo culture and the study of mammalian embryos during organogenesis

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

Effects of acrylonitrile on tissue glutathione concentrations in rat, mouse, and hamster

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12 December 2020

Influence of electrophilic character and glutathione depletion on chemical dysmorphogenesis in cultured rat embryos

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12 December 2020

Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro

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12 December 2020

Effect of glutathione depletion on the irreversible association of acrylonitrile with tissue macromolecules after oral administration to rats

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12 December 2020

In vivo biotransformation and biliary excretion of 1-14C-acrylonitrile in rats

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12 December 2020

Two routes of acrylonitrile metabolism

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12 December 2020

Irreversible protein binding of acrylonitrile

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12 December 2020

Identifiers

DOI

10.1007/BF01973303

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10 February 2018

PubMed ID

8494495

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10 February 2018