(Q48375362)

11 February 2018

review article

1 reference

title

The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. (English)

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11 February 2018

author name string

T K McIntosh

1

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11 February 2018

K E Saatman

2

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11 February 2018

R Raghupathi

3

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11 February 2018

D I Graham

4

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11 February 2018

D H Smith

5

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11 February 2018

V M Lee

6

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11 February 2018

J Q Trojanowski

7

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11 February 2018

publication date

1 August 1998

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11 February 2018

Neuropathology and Applied Neurobiology

published in

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11 February 2018

volume

24

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11 February 2018

issue

4

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11 February 2018

page(s)

251-267

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11 February 2018

Beta AP deposition and head trauma.

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21 January 2018

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Epidemiology of Alzheimer's Disease

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Mild posttraumatic hypothermia reduces mortality after severe controlled cortical impact in rats.

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Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory deficits.

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Structural and functional identification of regulatory regions and cis elements surrounding the nerve growth factor gene promoter

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Upregulation of nerve growth factor following cortical trauma.

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Regional levels of free fatty acids and Evans blue extravasation after experimental brain injury.

21 January 2018

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Early microvascular and neuronal consequences of traumatic brain injury: a light and electron microscopic study in rats

21 January 2018

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Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats.

21 January 2018

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Effects of CDP-choline treatment on neurobehavioral deficits after TBI and on hippocampal and neocortical acetylcholine release.

21 January 2018

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Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?

21 January 2018

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Excitotoxicity, free radicals, and cell membrane changes

21 January 2018

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Experimental brain injury induces expression of interleukin-1β mRNA in the rat brain

21 January 2018

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Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS.

21 January 2018

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Concussive brain injury is associated with a prolonged accumulation of calcium: a 45Ca autoradiographic study.

21 January 2018

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Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

21 January 2018

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Astrocytes are the major source of nerve growth factor upregulation following traumatic brain injury in the rat.

21 January 2018

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The antioxidant enzymes glutathione peroxidase and catalase increase following traumatic brain injury in the rat.

21 January 2018

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Production of tumor necrosis factor-alpha and interleukin-1beta by human cerebral microvascular endothelium after percussive trauma.

21 January 2018

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Microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression

21 January 2018

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The delayed neurobehavioural sequelae of traumatic brain injury

21 January 2018

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Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury

21 January 2018

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Alzheimer's disease: a study of epidemiological aspects.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Intracerebral inflammation after human brain contusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Up-regulation of intercellular adhesion molecule 1 in cerebral microvessels after cortical contusion trauma in a rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study.

21 January 2018

1 reference

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Postischemic glucose metabolism is modified in the hippocampal CA1 region depleted of excitatory input or pyramidal cells

21 January 2018

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Calcium-activated neutral protease in the peripheral nerve, which requires microM order Ca2+, and its effect on the neurofilament triplet

21 January 2018

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Induction of junD mRNA after transient forebrain ischemia in the rat. Effect of hypothermia.

21 January 2018

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Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition

21 January 2018

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George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury

21 January 2018

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Oxygen radicals in CNS damage

21 January 2018

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Microglia: a sensor for pathological events in the CNS

21 January 2018

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 January 2018

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

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Fluid percussion injury causes disruption of the septohippocampal pathway in the rat.

21 January 2018

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Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

21 January 2018

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Neuronotrophic activities in cerebrospinal fluid of head trauma patients.

21 January 2018

1 reference

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Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

A mechanistic analysis of nondisruptive axonal injury: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Genetic susceptibility and head injury as risk factors for Alzheimer's disease among community-dwelling elderly persons and their first-degree relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

21 January 2018

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Proto-oncogene transcription factors and epilepsy

21 January 2018

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Cytokines and neuropathology.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

21 January 2018

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Immunohistochemical study of calpain-mediated breakdown products to alpha-spectrin following controlled cortical impact injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis

21 January 2018

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Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

21 January 2018

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Regional changes in interstitial K+ and Ca2+ levels following cortical compression contusion trauma in rats.

21 January 2018

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Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels.

21 January 2018

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Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury

21 January 2018

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Cytokines and metabolic dysfunction after severe head injury

21 January 2018

1 reference

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Nerve growth factor and a fibroblast growth factor-like neurotrophic activity in cerebrospinal fluid of brain injured human patients.

21 January 2018

1 reference

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Distribution of calcium-activated protease calpain in the rat brain

21 January 2018

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Expression of c-fos in the Hippocampus Following Mild and Moderate Fluid Percussion Brain Injury

21 January 2018

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Extracranial complications of severe head injury

21 January 2018

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Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats

21 January 2018

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Apolipoprotein E polymorphism and Alzheimer's disease.

21 January 2018

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Diminished microtubule-associated protein 2 (MAP2) immunoreactivity following cortical impact brain injury.

21 January 2018

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The pathobiology of traumatically induced axonal injury in animals and humans: a review of current thoughts

21 January 2018

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DNA fragmentation and nuclear endonuclease activity in rat brain after severe closed head injury.

21 January 2018

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Suppression of cellular immune activity following severe head injury

21 January 2018

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Impairment of helper T-cell function following severe head injury

21 January 2018

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Cell-mediated immunity in severely head-injured patients: the role of suppressor lymphocytes and serum factors

21 January 2018

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Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat.

21 January 2018

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Lamin proteolysis facilitates nuclear events during apoptosis

21 January 2018

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Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat.

21 January 2018

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Effects of prolonged naloxone infusion in septic shock.

21 January 2018

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βA4 amyloid protein deposition in brain after head trauma

21 January 2018

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Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

21 January 2018

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Cytokines and the nervous system II: Actions and mechanisms of action

21 January 2018

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Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury.

21 January 2018

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Cold thoughts of death: the role of ICE proteases in neuronal cell death

21 January 2018

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Regulation by interleukin-1beta of formation of a line of delimiting astrocytes following prenatal trauma to the brain of the mouse.

21 January 2018

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Early detection of axonal injury after human head trauma using immunocytochemistry for beta-amyloid precursor protein

21 January 2018

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Oxidative stress in closed-head injury: brain antioxidant capacity as an indicator of functional outcome

21 January 2018

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Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue

21 January 2018

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Historical overview. Calcium, ischemia, and death of brain cells

21 January 2018

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Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis

21 January 2018

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Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease

21 January 2018

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Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury.

21 January 2018

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Combined fetal neural transplantation and nerve growth factor infusion: effects on neurological outcome following fluid-percussion brain injury in the rat.

21 January 2018

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Continuous c-fos expression precedes programmed cell death in vivo

21 January 2018

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Progressive atrophy and neuron death for one year following brain trauma in the rat.

21 January 2018

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Mild pre- and posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

21 January 2018

1 reference

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Microtubule-associated protein 2 levels decrease in hippocampus following traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Immunolocalization of heat shock protein after fluid percussive brain injury and relationship to breakdown of the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Association of apolipoprotein E polymorphism with outcome after head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid ?-protein and tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Ultrastructural evidence of axonal shearing as a result of lateral acceleration of the head in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

Increased phospholipase C activity after experimental brain injury.

21 January 2018

1 reference

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The generation of neurons and oligodendrocytes from a common precursor cell

21 January 2018

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Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production.

21 January 2018

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Cell death: the significance of apoptosis

21 January 2018

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Alterations of protein kinase C in rat hippocampus following traumatic brain injury.

21 January 2018

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Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: a casein zymography study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2990.1998.00121.X

10.1046/J.1365-2990.1998.00121.X

21 January 2018

Identifiers

DOI

1 reference

11 February 2018

1 reference

11 February 2018