(Q48386704)

11 February 2018

title

MSI-L gastric carcinomas share the hMLH1 methylation status of MSI-H carcinomas but not their clinicopathological profile. (English)

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11 February 2018

author

Carla Oliveira

2

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11 February 2018

José C. Machado

3

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11 February 2018

Fatima Carneiro

6

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11 February 2018

Manuel Sobrinho Simões

10

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11 February 2018

author name string

M Pinto

1

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11 February 2018

L Cirnes

4

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11 February 2018

J Tavares

5

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11 February 2018

R Hamelin

7

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11 February 2018

R Hofstra

8

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11 February 2018

R Seruca

9

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11 February 2018

publication date

1 December 2000

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11 February 2018

published in

Laboratory Investigation

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11 February 2018

volume

80

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11 February 2018

issue

12

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11 February 2018

page(s)

1915-1923

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11 February 2018

https://scigraph.springernature.com/pub.10.1038/labinvest.3780201

exact match

0 references

cites work

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

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MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas

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hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780201

Microsatellite instability and mismatch repair gene inactivation in sporadic pancreatic and colon tumours

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Origin of microsatellite instability in gastric cancer

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780201

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The DNA methylation paradox

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780201

The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different "target genes": a study of the TGFbeta RII, IGFII R, and BAX genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780201

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780201

Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780201

Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features

21 January 2018

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Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas

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Mutational analysis of MLH1 and MSH2 in 25 prospectively-acquired RER+ endometrial cancers

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Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

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Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer

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Microsatellite instability at multiple loci in gastric carcinoma: Clinicopathologic implications and prognosis

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MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

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7 January 2021

Distinct methylation pattern and microsatellite instability in sporadic gastric cancer

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7 January 2021

MSH2 andMLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis

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7 January 2021

10.1038/LABINVEST.3780201

Identifiers

DOI

1 reference

11 February 2018

PubMed ID

11140703

1 reference

11 February 2018