(Q48387511)

11 February 2018

title

Photoaffinity labeling approach to map the Taxol-binding site on the microtubule. (English)

1 reference

11 February 2018

author name string

G A Orr

1

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11 February 2018

S Rao

2

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11 February 2018

C S Swindell

3

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11 February 2018

D G Kingston

4

1 reference

11 February 2018

S B Horwitz

5

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11 February 2018

language of work or name

English

0 references

publication date

1 January 1998

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11 February 2018

published in

Methods in Enzymology

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11 February 2018

volume

298

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11 February 2018

page(s)

238-252

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11 February 2018

Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms

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Taxol binds to polymerized tubulin in vitro

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Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: reversibility, ligand stoichiometry, and competition.

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Direct photoaffinity labeling of tubulin with taxol

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Structure of tubulin at 6.5 A and location of the taxol-binding site.

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Structure of the alpha beta tubulin dimer by electron crystallography

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Unexpectedly Facile Hydrolysis of the 2-Benzoate Group of Taxol and Syntheses of Analogs with Increased Activities

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Differential Effects of Paclitaxel (Taxol) Analogs Modified at Positions C-2, C-7, and C-3' on Tubulin Polymerization and Polymer Stabilization: Identification of a Hyperactive Paclitaxel Derivative

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Structure-activity study of cytotoxicity and microtubule assembly in vitro by taxol and related taxanes

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Synthesis of a photoaffinity taxol analogue and its use in labeling tubulin

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[3H](azidophenyl)ureido taxoid photolabels peptide amino acids 281-304 of alpha-tubulin.

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Identifiers

DOI

1 reference

11 February 2018

PubMed ID

9751886

1 reference

11 February 2018