(Q48389526)

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Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.

scientific article published on 24 October 2006

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21 December 2019

Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert (English)

1 reference

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21 December 2019

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21 December 2019

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21 December 2019

Felix Hernandez

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21 December 2019

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Paloma Goñi-Oliver

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21 December 2019

Jesús Avila

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21 December 2019

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24 October 2006

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21 December 2019

Journal of Neurochemistry

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21 December 2019

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21 December 2019

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21 December 2019

1445-1455

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21 December 2019

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Role of tau protein in both physiological and pathological conditions.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Glycogen synthase kinase 3: a drug target for CNS therapies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Tau gene mutations and their effects.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

A molecular mechanism for the effect of lithium on development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Alzheimer's disease: a cell biological perspective

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Tau suppression in a neurodegenerative mouse model improves memory function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Chronic lithium enhances hippocampal long-term potentiation, but not neurogenesis, in the aged rat dentate gyrus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04139.X

21 January 2018

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