(Q48392041)

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Neuronal endosomal/lysosomal membrane destabilization activates caspases and induces abnormal accumulation of the lipid secondary messenger ceramide.

scientific article published in February 2003

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18 December 2019

Neuronal endosomal/lysosomal membrane destabilization activates caspases and induces abnormal accumulation of the lipid secondary messenger ceramide (English)

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18 December 2019

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8

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18 December 2019

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Kristen Ditaranto-Desimone

1

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18 December 2019

Mitsuo Saito

2

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18 December 2019

T L Tekirian

3

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18 December 2019

Mariko Saito

4

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18 December 2019

Martin Berg

5

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18 December 2019

Gene Dubowchik

6

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18 December 2019

Brian Soreghan

7

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18 December 2019

Neville Marks

9

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18 December 2019

Austin J Yang

10

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18 December 2019

publication date

1 February 2003

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18 December 2019

Brain Research Bulletin

1 reference

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18 December 2019

59

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18 December 2019

6

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18 December 2019

523-531

1 reference

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18 December 2019

Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease.

1 reference

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7 January 2021

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Ceramide-induced apoptosis occurs independently of caspases and is decreased by leupeptin

1 reference

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7 January 2021

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Lysosomal protease inhibitors induce meganeurites and tangle-like structures in entorhinohippocampal regions vulnerable to Alzheimer's disease

1 reference

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7 January 2021

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Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus

1 reference

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7 January 2021

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Photo-Oxidative Disruption of Lysosomal Membranes Causes Apoptosis of Cultured Human Fibroblasts

1 reference

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7 January 2021

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Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak

1 reference

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7 January 2021

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Colocalization of lysosomal hydrolase and beta-amyloid in diffuse plaques of the cerebellum and striatum in Alzheimer's disease and Down's syndrome

1 reference

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7 January 2021

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Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

1 reference

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7 January 2021

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Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

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7 January 2021

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Retinal age pigments generated by self-assembling lysosomotropic detergents

1 reference

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7 January 2021

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Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells

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7 January 2021

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Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents

1 reference

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7 January 2021

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Ceramide as an activator lipid of cathepsin D.

1 reference

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7 January 2021

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Regulation of a novel pathway for cell death by lysosomal aspartic and cysteine proteinases

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7 January 2021

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Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid

1 reference

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7 January 2021

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Sphingosine-induced apoptosis is dependent on lysosomal proteases

1 reference

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7 January 2021

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Determinants of the apoptotic response to lysosomal photodamage

1 reference

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7 January 2021

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Niemann-Pick disease

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7 January 2021

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Induction of endocytic vesicles by exogenous C(6)-ceramide

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7 January 2021

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Induction of cell death by the lysosomotropic detergent MSDH.

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7 January 2021

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OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron

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7 January 2021

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Uptake of oxidized LDL by macrophages results in partial lysosomal enzyme inactivation and relocation

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7 January 2021

based on heuristic

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Role of acidic sphingomyelinase in Fas/CD95-mediated cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2802%2900948-6

7 January 2021

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Recent advances on neuronal caspases in development and neurodegeneration

1 reference

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7 January 2021

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Activation of caspase-3 and apoptosis in cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2802%2900948-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell killing by lysosomotropic detergents

1 reference

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7 January 2021

based on heuristic

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Age-dependent change in activities of lysosomal enzymes in rat brain

1 reference

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7 January 2021

based on heuristic

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Increased expression of cathepsins E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy-terminal fragments of Alzheimer amyloid precursor protein.

1 reference

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7 January 2021

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The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review

1 reference

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7 January 2021

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The lysosomal system in neurons. Involvement at multiple stages of Alzheimer's disease pathogenesis

1 reference

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7 January 2021

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An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins

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Starvation-induced autophagocytosis paradoxically decreases the susceptibility to oxidative stress of the extremely oxidative stress-sensitive NIT insulinoma cells

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7 January 2021

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Inhibition of cathepsin D prevents free-radical-induced apoptosis in rat cardiomyocytes

1 reference

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7 January 2021

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Programmed cell death and the caspases.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases: intracellular signaling by proteolysis

1 reference

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7 January 2021

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Cathepsin B-mediated activation of the proinflammatory caspase-11.

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Quantitation of lipids by charring on thin-layer plates and scintillation quenching: application to ceramide determination

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

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7 January 2021

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Age-related Macular Degeneration

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7 January 2021

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The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole

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A relationship between multidrug resistance and growth-state dependent cytotoxicity of the lysosomotropic detergent N-dodecylimidazole

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7 January 2021

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Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells

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Lysosomal ceroid depletion by drugs: therapeutic implications for a hereditary neurodegenerative disease of childhood

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Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity

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7 January 2021

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Overexpression of cation-dependent mannose 6-phosphate receptor prevents cell death induced by serum deprivation in PC12 cells

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Identifiers

10.1016/S0361-9230(02)00948-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576150%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576150%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

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