(Q48403910)

11 February 2018

title

Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons. (English)

1 reference

11 February 2018

1 reference

Isamu Aiba

1

1 reference

11 February 2018

C William Shuttleworth

series ordinal

2

1 reference

11 February 2018

language of work or name

English

0 references

publication date

20 August 2012

1 reference

11 February 2018

published in

Journal of Physiology

1 reference

11 February 2018

volume

590

1 reference

11 February 2018

issue

22

1 reference

11 February 2018

page(s)

5877-5893

1 reference

11 February 2018

Synaptic release and extracellular actions of Zn2+ limit propagation of spreading depression and related events in vitro and in vivo

cites work

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Spreading depression: imaging and blockade in the rat neocortical brain slice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Longitudinal depolarization gradients along the somatodendritic axis of CA1 pyramidal cells: a novel feature of spreading depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Sustained dendritic gradients of Ca2+ induced by excitatory amino acids in CA1 hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Membrane currents in CA1 pyramidal cells during spreading depression (SD) and SD-like hypoxic depolarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Zn2+ influx is critical for some forms of spreading depression in brain slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Protective effect of ifenprodil against spreading depression in the mouse entorhinal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Changes in membrane potential and the intracellular calcium concentration during CSD and OGD in layer V and layer II/III mouse cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Analysis of potential shifts associated with recurrent spreading depression and prolonged unstable spreading depression induced by microdialysis of elevated K+ in hippocampus of anesthetized rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Propagation of spreading depression among dendrites and somata of the same cell population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

P/Q Ca2+ channel blockade stops spreading depression and related pyramidal neuronal Ca2+ rise in hippocampal organ culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

A role for glutamate and glia in the fast network oscillations preceding spreading depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

NR3A-containing NMDARs promote neurotransmitter release and spike timing-dependent plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

The use of fura-2 for estimating Ca buffers and Ca fluxes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Effects of pan- and subtype-selective N-methyl-D-aspartate receptor antagonists on cortical spreading depression in the rat: therapeutic potential for migraine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Repetitive spreading depression-like events result in cell damage in juvenile hippocampal slice cultures maintained in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Glutamate release in severe brain ischaemia is mainly by reversed uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Preliminary evidence that ketamine inhibits spreading depolarizations in acute human brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Vasoconstrictive neurovascular coupling during focal ischemic depolarizations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Ion regulation in the brain: implications for pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Cortical spreading depression causes and coincides with tissue hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Metabolic and perfusion responses to recurrent peri-infarct depolarization during focal ischemia in the Spontaneously Hypertensive Rat: dominant contribution of sporadic CBF decrements to infarct expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Localized loss of Ca2+ homeostasis in neuronal dendrites is a downstream consequence of metabolic compromise during extended NMDA exposures

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Persisting modification of dendritic calcium influx by excitatory amino acid stimulation in isolated Ca1 neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Transient swelling, acidification, and mitochondrial depolarization occurs in neurons but not astrocytes during spreading depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.234476

Cumulative effects of glutamate microstimulation on Ca(2+) responses of CA1 hippocampal pyramidal neurons in slice

21 January 2018

1 reference

12 December 2020

Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons.

1 reference

12 December 2020

Mechanisms of spreading depression and hypoxic spreading depression-like depolarization

1 reference

12 December 2020

Fast vesicle recycling supports neurotransmission during sustained stimulation at hippocampal synapses.

1 reference

12 December 2020

Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection.

1 reference

12 December 2020

A new generation of Ca2+ indicators with greatly improved fluorescence properties

1 reference

12 December 2020

Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons

1 reference

12 December 2020

10.1113/JPHYSIOL.2012.234476

Identifiers

DOI

1 reference

11 February 2018

PMC publication ID

3528997

0 references

1 reference

11 February 2018