(Q48408724)

English

The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood-brain barrier in the pharmaceutical industry--background and current status in the drug discovery process.

scientific article published in June 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood-brain barrier in the pharmaceutical industry--background and current status in the drug discovery process. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

blood–brain barrier

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Stefan Lundquist

1

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

Mila Renftel

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

publication date

1 June 2002

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

Vascular Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

38

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

6

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

355-364

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

Bovine brain microvessel endothelial cell monolayers as a model system for the blood-brain barrier

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Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis

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An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1537-1891%2802%2900203-3

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Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes

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7 January 2021

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An improved low-permeability in vitro-model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol

1 reference

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7 January 2021

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The blood-brain barrier in vitro: Ten years of research on microvessels isolated from the brain.

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Blood-brain barrier abnormalities in longstanding multiple sclerosis lesions. An immunohistochemical study

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Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture.

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Hypoxia Increases the Susceptibility to Oxidant Stress and the Permeability of the Blood‐Brain Barrier Endothelial Cell Monolayer

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Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)

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Carrier-mediated delivery of metabotrophic glutamate receptor ligands to the central nervous system: structural tolerance and potential of the L-system amino acid transporter at the blood-brain barrier

1 reference

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F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: effects of cyclic AMP and astrocytic factors

1 reference

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A cell culture model of the blood-brain barrier

1 reference

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inferred from DOI database lookup

Identifiers

10.1016/S1537-1891(02)00203-3

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/12529930

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