(Q48412703)

11 February 2018

title

A novel alpha-helix in the first fibronectin type III repeat of the neural cell adhesion molecule is critical for N-glycan polysialylation (English)

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11 February 2018

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author name string

Shalu Shiv Mendiratta

1

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Francisco G Hernandez-Guzman

3

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Brett E Close

4

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Arnon Lavie

5

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Karen J Colley

6

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language of work or name

English

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publication date

26 September 2006

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11 February 2018

Journal of Biological Chemistry

published in

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volume

281

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issue

47

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page(s)

36052-36059

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11 February 2018

Roles, regulation, and mechanism of polysialic acid function during neural development

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Glycans and neural cell interactions

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Polysialic acid directs tumor cell growth by controlling heterophilic neural cell adhesion molecule interactions.

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Polysialyltransferases: major players in polysialic acid synthesis on the neural cell adhesion molecule

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Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior

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Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule.

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Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning.

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In vivo autopolysialylation and localization of the polysialyltransferases PST and STX.

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Polysialyltransferase-1 autopolysialylation is not requisite for polysialylation of neural cell adhesion molecule

21 January 2018

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Trafficking of lysosomal enzymes in normal and disease states

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Oligosaccharides containing beta 1,4-linked N-acetylgalactosamine, a paradigm for protein-specific glycosylation

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A cluster of basic amino acids within an alpha-helix is essential for alpha-subunit recognition by the glycoprotein hormone N-acetylgalactosaminyltransferase

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Molecular basis of recognition by the glycoprotein hormone-specific N-acetylgalactosamine-transferase

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Specific amino acids in the first fibronectin type III repeat of the neural cell adhesion molecule play a role in its recognition and polysialylation by the polysialyltransferase ST8Sia IV/PST.

21 January 2018

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The minimal structural domains required for neural cell adhesion molecule polysialylation by PST/ST8Sia IV and STX/ST8Sia II.

21 January 2018

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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

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21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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21 January 2018

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Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases

21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M608073200

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11 February 2018

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11 February 2018