(Q48451001)

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Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia.

scientific article published on 21 November 2014

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25413451%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia (English)

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Europe PubMed Central

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23 February 2020

cerebral infarction

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based on heuristic

inferred from title

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based on heuristic

inferred from title

2

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Europe PubMed Central

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23 February 2020

Fariba Khodagholi

3

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23 February 2020

Alireza Sarkaki

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23 February 2020

Mahdi Goudarzvand

4

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23 February 2020

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Ghorbangol Ashabi

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23 February 2020

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21 November 2014

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23 February 2020

Metabolic Brain Disease

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23 February 2020

30

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23 February 2020

3

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23 February 2020

747-754

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23 February 2020

Catalase in vitro

1 reference

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21 January 2018

Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: interference of AMPK/PGC-1α pathway.

1 reference

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21 January 2018

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21 January 2018

Passage of spermidine across the blood-brain barrier in short recirculation periods following global cerebral ischemia: effects of mild hyperthermia.

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21 January 2018

Pathobiology of ischaemic stroke: an integrated view

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21 January 2018

The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro.

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21 January 2018

Tissue sulfhydryl groups

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21 January 2018

Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation

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21 January 2018

Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats

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21 January 2018

Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells

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21 January 2018

Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells

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21 January 2018

Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages

1 reference

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21 January 2018

Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway.

1 reference

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21 January 2018

Effects of insulin and oral anti-diabetic agents on glucose metabolism, vascular dysfunction and skeletal muscle inflammation in type 2 diabetic subjects

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21 January 2018

Curcumin loaded solid lipid nanoparticles: an efficient formulation approach for cerebral ischemic reperfusion injury in rats

1 reference

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21 January 2018

AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death

1 reference

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21 January 2018

Gemfibrozil pretreatment proved protection against acute restraint stress-induced changes in the male rats' hippocampus

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21 January 2018

AICAR (5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside) increases the production of toxic molecules and affects the profile of cytokines release in LPS-stimulated rat primary microglial cultures

1 reference

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21 January 2018

Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide.

1 reference

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21 January 2018

Contribution of downregulation of L-type calcium currents to delayed neuronal death in rat hippocampus after global cerebral ischemia and reperfusion.

1 reference

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21 January 2018

Effects of Metformin in Experimental Stroke

1 reference

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21 January 2018

Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation.

1 reference

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21 January 2018

Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity.

1 reference

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21 January 2018

Function of the master energy regulator adenosine monophosphate-activated protein kinase in stroke

1 reference

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21 January 2018

Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

1 reference

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21 January 2018

Organizational update: World Health Organization

1 reference

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21 January 2018

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9632-2

21 January 2018

Gemfibrozil pretreatment affecting antioxidant defense system and inflammatory, but not Nrf-2 signaling pathways resulted in female neuroprotection and male neurotoxicity in the rat models of global cerebral ischemia-reperfusion

1 reference

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21 January 2018

Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia

1 reference

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21 January 2018

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

1 reference

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21 January 2018

AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model

1 reference

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21 January 2018

A new model of bilateral hemispheric ischemia in the unanesthetized rat

1 reference

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21 January 2018

Activation of the AMP-activated protein kinase reduces inflammatory nociception

1 reference

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21 January 2018

Stroke after cardiac surgery: short- and long-term outcomes

1 reference

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21 January 2018

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

1 reference

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21 January 2018

AMP-activated protein kinase: a potential player in Alzheimer's disease

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21 January 2018

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia

1 reference

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21 January 2018

Comparable studies of the incidence of stroke and its pathological types: results from an international collaboration. International Stroke Incidence Collaboration.

1 reference

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21 January 2018

Ginkgo biloba prevents transient global ischemia-induced delayed hippocampal neuronal death through antioxidant and anti-inflammatory mechanism

1 reference

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21 January 2018

The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells

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21 January 2018

Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.

1 reference

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21 January 2018

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

1 reference

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21 January 2018

Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death

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21 January 2018

Alleviation of transient global ischemia/reperfusion-induced brain injury in rats with 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose isolated from Mangifera indica

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21 January 2018

Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling

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21 January 2018

Metformin protects rat hepatocytes against bile acid-induced apoptosis

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21 January 2018

AMPK synergizes with the combined treatment of 1'-acetoxychavicol acetate and sodium butyrate to upregulate phase II detoxifying enzyme activities

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21 January 2018

The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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21 January 2018

Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells

1 reference

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21 January 2018

AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25413451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved myocardial perfusion in chronic diabetic mice by the up-regulation of pLKB1 and AMPK signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25413451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiatherogenic properties of metformin: the experimental evidence.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25413451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25413451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tert-Butylhydroquinone pretreatment protects kidney from ischemia-reperfusion injury

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11011-014-9632-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25413451%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25413451%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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