(Q48485626)

English

The immunophilin ligand GPI1046 protects neurons from the lethal effects of the HIV-1 proteins gp120 and Tat by modulating endoplasmic reticulum calcium load.

scientific article published in July 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

The immunophilin ligand GPI1046 protects neurons from the lethal effects of the HIV-1 proteins gp120 and Tat by modulating endoplasmic reticulum calcium load. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

endoplasmic reticulum

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author name string

Emily Caporello

1

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Avindra Nath

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

John Slevin

3

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

David Galey

4

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Greg Hamilton

5

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Larry Williams

6

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Joseph P Steiner

7

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Norman J Haughey

8

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

language of work or name

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publication date

1 July 2006

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Journal of Neurochemistry

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

98

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

1

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

146-155

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis

1 reference

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21 January 2018

The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells

1 reference

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21 January 2018

The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence

1 reference

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21 January 2018

The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration.

1 reference

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21 January 2018

The inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by macrocyclic lactones and cyclosporin A.

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21 January 2018

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

1 reference

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21 January 2018

Immunophilin ligands promote penile neurogenesis and erection recovery after cavernous nerve injury

1 reference

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21 January 2018

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

1 reference

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21 January 2018

gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors

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21 January 2018

The neuropathogenesis of AIDS

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21 January 2018

Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons

1 reference

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21 January 2018

Immunophilins: beyond immunosuppression

1 reference

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21 January 2018

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

1 reference

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21 January 2018

Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat

1 reference

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21 January 2018

HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity

1 reference

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21 January 2018

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.

1 reference

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21 January 2018

Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia

1 reference

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21 January 2018

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

1 reference

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21 January 2018

Role of Na+/H+ exchangers, excitatory amino acid receptors and voltage-operated Ca2+ channels in human immunodeficiency virus type 1 gp120-mediated increases in intracellular Ca2+ in human neurons and astrocytes

1 reference

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21 January 2018

Inositol phosphates and intracellular calcium after bradykinin stimulation in fibroblasts from young, normal aged and Alzheimer donors

1 reference

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21 January 2018

Immunolocalization of HIV envelope gp120 in HIV encephalitis with dementia.

1 reference

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21 January 2018

HIV-1 infection and AIDS: consequences for the central nervous system

1 reference

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21 January 2018

Disturbance of membrane function preceding ischemic delayed neuronal death in the gerbil hippocampus

1 reference

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21 January 2018

Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes

1 reference

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21 January 2018

Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03863.X

21 January 2018

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03863.X

21 January 2018

Immunophilin Modulation of Calcium Channel Gating

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03863.X

21 January 2018

Cell death in HIV dementia

1 reference

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21 January 2018

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

1 reference

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21 January 2018

The small molecule FKBP ligand GPI 1046 induces partial striatal re-innervation after intranigral 6-hydroxydopamine lesion in rats

1 reference

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21 January 2018

Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues

1 reference

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21 January 2018

Tacrolimus: a further update of its use in the management of organ transplantation

1 reference

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21 January 2018

The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site

1 reference

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21 January 2018

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03863.X

21 January 2018

Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

1 reference

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21 January 2018

Immunosuppressive and non-immunosuppressive immunophilin ligands improve H(2)O(2)-induced cell damage by increasing glutathione levels in NG108-15 cells

1 reference

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21 January 2018

Neuroprotective and antioxidant properties of FKBP-binding immunophilin ligands are independent on the FKBP12 pathway in human cells

1 reference

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21 January 2018

Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort

1 reference

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21 January 2018

Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1

1 reference

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21 January 2018

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

1 reference

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SYK and LYN mediate B-cell receptor-independent calcium-induced apoptosis in DT-40 lymphoma B-cells

1 reference

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21 January 2018

Mobilization of intracellular calcium stores participates in the rise of [Ca2+]iand the toxic actions of the HIV coat protein GP120

1 reference

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21 January 2018

Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1

1 reference

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Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor

1 reference

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21 January 2018

HIV-1 coat protein gp120-induced increases in levels of intrasynaptosomal calcium

1 reference

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21 January 2018

Immediate and neurotoxic effects of HIV protein gp120 act through CXCR4 receptor

1 reference

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21 January 2018

Identifiers

10.1111/J.1471-4159.2006.03863.X

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/16805804

ResearchGate publication ID

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