(Q48487103)

English

DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis.

scientific article published in January 2002

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scholarly article

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis. (English)

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

amyotrophic lateral sclerosis

0 references

author name string

Arif Y Shaikh

1

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

Lee J Martin

2

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

publication date

1 January 2002

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

NeuroMolecular Medicine

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

2

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

1

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

47-60

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

https://scigraph.springernature.com/pub.10.1007/s12017-002-0038-7

0 references

Apoptosis of retrogradely degenerating neurons occurs in association with the accumulation of perikaryal mitochondria and oxidative damage to the nucleus

1 reference

https://api.crossref.org/works/10.1007%2FS12017-002-0038-7

21 January 2018

A new hypothesis of the etiology of amyotrophic lateral sclerosis. The DNA hypothesis

1 reference

https://api.crossref.org/works/10.1007%2FS12017-002-0038-7

21 January 2018

Molecular interaction map of the mammalian cell cycle control and DNA repair systems

1 reference

https://api.crossref.org/works/10.1007%2FS12017-002-0038-7

21 January 2018

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice, the motor system, and human motor neuron pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficient DNA repair in amyotrophic lateral sclerosis cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and amino-terminal amino acid sequence of an apurinic/apyrimidinic endonuclease from calf thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases a

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALS, SOD and peroxynitrite

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53, the cellular gatekeeper for growth and division

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis: evidence for the implication of the p53 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Par-4: an emerging pivotal player in neuronal apoptosis and neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening of AP endonuclease as a candidate gene for amyotrophic lateral sclerosis (ALS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for DNA damage in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential cellular and subcellular expression of the human multifunctional apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of mature spinal motor neurons and single-cell analysis using the comet assay of early low-level DNA damage induced in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in amyotrophic lateral sclerosis: a review of the evidence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis related antigen, Le(Y) and nick-end labeling are positive in spinal motor neurons in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal cell death in nervous system development, disease, and injury (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of N-methylpurines in DNA from lymphocytes of patients with amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neuronal death in sporadic amyotrophic lateral sclerosis (ALS) is not apoptotic. A comparative study of ALS and chronic aluminium chloride neurotoxicity in New Zealand white rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic damage and its repair in young and aging brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Instability and decay of the primary structure of DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidemiology of motor neuron diseases: a review of recent studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of Bax protein and increased DNA degradation in ALS spinal cord motor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant AP endonuclease in patients with amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12230304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12017-002-0038-7

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12230304

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